Ordered dephosphorylation initiated by the selective proteolysis of cyclin B drives mitotic exit

Ordered dephosphorylation initiated by the selective proteolysis of cyclin B drives mitotic exit

APC/C-mediated proteolysis of cyclin B and securin promotes anaphase entry, inactivating CDK1 and permitting chromosome segregation, respectively. Reduction of CDK1 activity relieves inhibition of the CDK1-counteracting phosphatases PP1 and PP2A-B55, allowing wide-spread dephosphorylation of substra...

Volledige beschrijving

Bibliografische gegevens
Hoofdauteurs:	Holder, J, Mohammed, S, Barr, FA
Formaat:	Journal article
Taal:	English
Gepubliceerd in:	eLife Sciences Publications 2020

Gelijkaardige items

Quantitative analysis of regulated proteolysis and protein dephosphorylation during mitotic exit
door: Holder, J
Gepubliceerd in: (2018)

A PP2A-B55 recognition signal controls substrate dephosphorylation kinetics during mitotic exit
door: Cundell, M, et al.
Gepubliceerd in: (2016)

PP1 promotes cyclin B destruction and the metaphase-anaphase transition by dephosphorylating CDC20
door: Bancroft, J, et al.
Gepubliceerd in: (2020)

PP2A/B55 and Fcp1 regulate Greatwall and Ensa dephosphorylation during mitotic exit.
door: Hégarat, N, et al.
Gepubliceerd in: (2014)

Mitotic exit in two dimensions.
door: Tóth, A, et al.
Gepubliceerd in: (2007)

Mitotic exit in mammalian cells.
door: Kapuy, O, et al.
Gepubliceerd in: (2009)

Getting out of mitosis: Spatial and temporal control of mitotic exit and cytokinesis by PP1 and PP2A
door: Holder, J, et al.
Gepubliceerd in: (2019)

Regulation of mitotic exit in Saccharomyces cerevisiae
door: Stegmeier, Frank P. (Frank Peter), 1975-
Gepubliceerd in: (2006)

A cyclin without cyclin-dependent kinases: cyclin F controls genome stability through ubiquitin-mediated proteolysis
door: D'Angiolella, V, et al.
Gepubliceerd in: (2012)

A cyclin without cyclin-dependent kinases: cyclin F controls genome stability through ubiquitin-mediated proteolysis.
door: D'Angiolella, V, et al.
Gepubliceerd in: (2013)

A cyclin without cyclin-dependent kinases: Cyclin F controls genome stability through ubiquitin-mediated proteolysis
door: D'Angiolella, V, et al.
Gepubliceerd in: (2013)

Control of the mitotic exit network during meiosis
door: Attner, Michelle Andrea, et al.
Gepubliceerd in: (2012)

Stochastic modelling of mitotic exit in mammalian cells
door: He, E, et al.
Gepubliceerd in: (2010)

Role for cyclin-dependent kinase 2 in mitosis exit.
door: D'Angiolella, V, et al.
Gepubliceerd in: (2001)

Irreversibility of mitotic exit is the consequence of systems-level feedback.
door: López-Avilés, S, et al.
Gepubliceerd in: (2009)

Identification of novel regulators of mitotic exit in Saccharomyces cerevisiae
door: D'Aquino, Katharine E
Gepubliceerd in: (2008)

Modeling and simulation of Mitotic exit control in budding yeast
door: Tan, Meng How.
Gepubliceerd in: (2008)

Regulation and functions of Cdc14 in mitotic exit in Saccharomyces cerevisiae
door: Tomson, Brett N
Gepubliceerd in: (2009)

The Mitotic Exit Network detects spindle position and anaphase entry
door: Campbell, Ian Winsten.
Gepubliceerd in: (2019)

A critical analysis of a mathematical model for mitotic exit
door: Freire, P, et al.
Gepubliceerd in: (2011)

Hsp90 is required to localise cyclin B and Msps/ch-TOG to the mitotic spindle in Drosophila and humans.
door: Basto, R, et al.
Gepubliceerd in: (2007)

Regulation of the localization of Lte1, a S. cerevisiae mitotic exit activator
door: Seshan, Anupama
Gepubliceerd in: (2006)

Spindle pole bodies function as signal amplifiers in the Mitotic Exit Network
door: Campbell, Ian W, et al.
Gepubliceerd in: (2021)

Spatial and temporal coordination of genome segregation with activation of the Mitotic Exit Network
door: Rock, Jeremy M. (Jeremy Michael)
Gepubliceerd in: (2013)

Mathematical modelling of mitotic exit control in budding yeast cell cycle
door: Freire, P, et al.
Gepubliceerd in: (2012)

Mitotic exit in two dimensions (vol 248, pg 560, 2007)
door: Toth, A, et al.
Gepubliceerd in: (2008)

E2F1 proteolysis via SCF-cyclin F underlies synthetic lethality between cyclin F loss and Chk1 inhibition
door: Burdova, K, et al.
Gepubliceerd in: (2019)

Multisite phosphoregulation of Cdc25 activity refines the mitotic entrance and exit switches.
door: Lu, L, et al.
Gepubliceerd in: (2012)

Regulation of the mitotic exit network components Tem1 and Cde 15 in Saccharomyces cerevisiae
door: Bardin, Allison J. (Allison Johanna), 1975-
Gepubliceerd in: (2005)

Computational modelling of mitotic exit in budding yeast: the role of separase and Cdc14 endocycles.
door: Vinod, P, et al.
Gepubliceerd in: (2011)

Repo-Man coordinates chromosomal reorganization with nuclear envelope reassembly during mitotic exit.
door: Vagnarelli, P, et al.
Gepubliceerd in: (2011)

SCF(Cyclin F) controls centrosome homeostasis and mitotic fidelity through CP110 degradation.
door: D'Angiolella, V, et al.
Gepubliceerd in: (2010)

Cyclin A triggers mitosis either via the greatwall kinase pathway or cyclin B
door: Hégarat, N, et al.
Gepubliceerd in: (2020)

The Mitotic Exit Network integrates temporal and spatial signals by distributing regulation across multiple components
door: Zhou, Xiaoxue, et al.
Gepubliceerd in: (2020)

Selective dephosphorylation by PP2A-B55 directs the meiosis I-meiosis II transition in oocytes
door: Swartz, S Zachary, et al.
Gepubliceerd in: (2022)

EXOCYTOSIS IN MOUSE PANCREATIC B-CELLS IS REGULATED BY THE BALANCE BETWEEN PHOSPHORYLATION AND DEPHOSPHORYLATION
door: Rorsman, P, et al.
Gepubliceerd in: (1993)

Spindle Position Is Coordinated with Cell-Cycle Progression through Establishment of Mitotic Exit-Activating and -Inhibitory Zones
door: Chan, Leon Y., et al.
Gepubliceerd in: (2013)

Lte1 promotes mitotic exit by controlling the localization of the spindle position checkpoint kinase Kin4
door: Chan, Leon Y., et al.
Gepubliceerd in: (2012)

"Licensed to kill": tyrosine dephosphorylation and Bak activation.
door: Fox, J, et al.
Gepubliceerd in: (2011)

Vascular K ATP channels: dephosphorylation and deactivation.
door: Tammaro, P
Gepubliceerd in: (2009)