Visualizing the architectures and interactions of nuclear receptors

Nuclear receptors (NRs) are master regulators of broad genetic programs in metazoans. These programs are regulated in part by the small-molecule ligands that bind NRs and modulate their interactions with transcriptional coregulatory factors. X-ray crystallography is now delivering more complete pict...

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Detalhes bibliográficos
Main Authors: Khorasanizadeh, S, Rastinejad, F
Formato: Journal article
Idioma:English
Publicado em: Oxford University Press 2016