Structural features underlying T-cell receptor sensitivity to concealed MHC class I micropolymorphisms.
Polymorphic differences distinguishing MHC class I subtypes often permit the presentation of shared epitopes in conformationally identical formats but can affect T-cell repertoire selection, differentially impacting autoimmune susceptibilities and viral clearance in vivo. The molecular mechanisms un...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
2012
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Structural features underlying T-cell receptor sensitivity to concealed MHC class I micropolymorphisms.
Published 2012
Journal article