Dupilumab efficacy and safety in moderate-to-severe uncontrolled Asthma

Dupilumab is a fully human anti-interleukin-4 receptor α monoclonal antibody that blocks both interleukin-4 and interleukin-13 signaling. We assessed its efficacy and safety in patients with uncontrolled asthma.We randomly assigned 1902 patients 12 years of age or older with uncontrolled asthma in a...

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Main Authors: Castro, M, Corren, J, Pavord, I, Maspero, J, Wenzel, S, Rabe, K, Busse, W, Ford, L, Sher, L, FitzGerald, J, Katelaris, C, Tohda, Y, Zhang, B, Staudinger, H, Pirozzi, G, Amin, N, Ruddy, M, Akinlade, B, Khan, A, Chao, J, Martincova, R, Graham, N, Hamilton, J, Swanson, B, Stahl, N, Yancopoulos, G, Teper, A
格式: Journal article
语言:English
出版: Massachusetts Medical Society 2018

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