A whole blood monokine-based reporter assay provides a sensitive and robust measurement of the antigen-specific T cell response.

BACKGROUND: The ability to measure T-cell responses to antigens is proving critical in the field of vaccine development and for understanding immunity to pathogens, allergens and self-antigens. Although a variety of technologies exist for this purpose IFNγ-ELISpot assays are widely used because of...

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Detalles Bibliográficos
Main Authors: Chakera, A, Bennett, S, Cornall, R
Formato: Journal article
Idioma:English
Publicado: 2011