Neuroimaging in dementia.
Over the last few years, advances in neuroimaging have generated biomarkers, which increase diagnostic certainty, provide valuable information about prognosis, and suggest a particular pathology underlying the clinical dementia syndrome. We aim to review the evidence for use of already established i...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
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2014
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| _version_ | 1826259231444041728 |
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| author | Valkanova, V Ebmeier, K |
| author_facet | Valkanova, V Ebmeier, K |
| author_sort | Valkanova, V |
| collection | OXFORD |
| description | Over the last few years, advances in neuroimaging have generated biomarkers, which increase diagnostic certainty, provide valuable information about prognosis, and suggest a particular pathology underlying the clinical dementia syndrome. We aim to review the evidence for use of already established imaging modalities, along with selected techniques that have a great potential to guide clinical decisions in the future. We discuss structural, functional and molecular imaging, focusing on the most common dementias: Alzheimer's disease, fronto-temporal dementia, dementia with Lewy bodies and vascular dementia. Finally, we stress the importance of conducting research using representative cohorts and in a naturalistic set up, in order to build a strong evidence base for translating imaging methods for a National Health Service. If we assess a broad range of patients referred to memory clinic with a variety of imaging modalities, we will make a step towards accumulating robust evidence and ultimately closing the gap between the dramatic advances in neurosciences and meaningful clinical applications for the maximum benefit of our patients. |
| first_indexed | 2024-03-06T18:46:37Z |
| format | Journal article |
| id | oxford-uuid:0ebc753c-243c-4969-8d0d-d307e62d4a2c |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T18:46:37Z |
| publishDate | 2014 |
| record_format | dspace |
| spelling | oxford-uuid:0ebc753c-243c-4969-8d0d-d307e62d4a2c2022-03-26T09:47:30ZNeuroimaging in dementia.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:0ebc753c-243c-4969-8d0d-d307e62d4a2cEnglishSymplectic Elements at Oxford2014Valkanova, VEbmeier, KOver the last few years, advances in neuroimaging have generated biomarkers, which increase diagnostic certainty, provide valuable information about prognosis, and suggest a particular pathology underlying the clinical dementia syndrome. We aim to review the evidence for use of already established imaging modalities, along with selected techniques that have a great potential to guide clinical decisions in the future. We discuss structural, functional and molecular imaging, focusing on the most common dementias: Alzheimer's disease, fronto-temporal dementia, dementia with Lewy bodies and vascular dementia. Finally, we stress the importance of conducting research using representative cohorts and in a naturalistic set up, in order to build a strong evidence base for translating imaging methods for a National Health Service. If we assess a broad range of patients referred to memory clinic with a variety of imaging modalities, we will make a step towards accumulating robust evidence and ultimately closing the gap between the dramatic advances in neurosciences and meaningful clinical applications for the maximum benefit of our patients. |
| spellingShingle | Valkanova, V Ebmeier, K Neuroimaging in dementia. |
| title | Neuroimaging in dementia. |
| title_full | Neuroimaging in dementia. |
| title_fullStr | Neuroimaging in dementia. |
| title_full_unstemmed | Neuroimaging in dementia. |
| title_short | Neuroimaging in dementia. |
| title_sort | neuroimaging in dementia |
| work_keys_str_mv | AT valkanovav neuroimagingindementia AT ebmeierk neuroimagingindementia |