Induction of immunological tolerance/hyporesponsiveness in baboons with a nondepleting CD4 antibody.
Tolerance induction with anti-CD4 Abs is well established in rodent transplant and autoimmune disease models, but has yet to be demonstrated in non-human primates or in clinical studies. In retrospect, failure of anti-CD4 Abs to induce tolerance in primates may be technical, a consequence of insuffi...
Main Authors: | Winsor-Hines, D, Merrill, C, O'Mahony, M, Rao, P, Cobbold, S, Waldmann, H, Ringler, D, Ponath, P |
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Format: | Journal article |
Language: | English |
Published: |
2004
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