Epidemiology of the Zika virus outbreak in the Cabo Verde Islands, West Africa

<p><strong>Introduction:</strong> The Zika virus (ZIKV) outbreak in the island nation of Cabo Verde was of unprecedented magnitude in Africa and the first to be associated with microcephaly in the continent.</p> <p><strong>Methods:</strong> Using a simple m...

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Main Authors: Lourenço, J, de Lourdes Monteiro, M, Valdez, Y, Monteiro Rodrigues, J, Pybus, O, Rodrigues Faria, N
Format: Journal article
Language:English
Published: Public Library of Science 2018
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author Lourenço, J
de Lourdes Monteiro, M
Valdez, Y
Monteiro Rodrigues, J
Pybus, O
Rodrigues Faria, N
author_facet Lourenço, J
de Lourdes Monteiro, M
Valdez, Y
Monteiro Rodrigues, J
Pybus, O
Rodrigues Faria, N
author_sort Lourenço, J
collection OXFORD
description <p><strong>Introduction:</strong> The Zika virus (ZIKV) outbreak in the island nation of Cabo Verde was of unprecedented magnitude in Africa and the first to be associated with microcephaly in the continent.</p> <p><strong>Methods:</strong> Using a simple mathematical framework we present a first epidemiological assessment of attack and observation rates from 7,580 ZIKV notified cases and 18 microcephaly reports between July 2015 and May 2016.</p> <p><strong>Results:</strong> In line with observations from the Americas and elsewhere, the single-wave Cabo Verdean ZIKV epidemic was characterized by a basic reproductive number of 1.85 (95% CI, 1.5 – 2.2), with overall the attack rate of 51.1% (range 42.1 – 61.1) and observation rate of 2.7% (range 2.29 – 3.33).</p> <p><strong>Conclusion:</strong> Current herd-immunity may not be sufficient to prevent future small-to-medium epidemics in Cabo Verde. Together with a small observation rate, these results highlight the need for rapid and integrated epidemiological, molecular and genomic surveillance to tackle forthcoming outbreaks of ZIKV and other arboviruses.</p>
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spelling oxford-uuid:0edbd8b9-e3c8-4c29-a7a2-7a73435e3a5b2023-07-05T14:00:44ZEpidemiology of the Zika virus outbreak in the Cabo Verde Islands, West AfricaJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:0edbd8b9-e3c8-4c29-a7a2-7a73435e3a5bEnglishSymplectic ElementsPublic Library of Science2018Lourenço, Jde Lourdes Monteiro, MValdez, YMonteiro Rodrigues, JPybus, ORodrigues Faria, N<p><strong>Introduction:</strong> The Zika virus (ZIKV) outbreak in the island nation of Cabo Verde was of unprecedented magnitude in Africa and the first to be associated with microcephaly in the continent.</p> <p><strong>Methods:</strong> Using a simple mathematical framework we present a first epidemiological assessment of attack and observation rates from 7,580 ZIKV notified cases and 18 microcephaly reports between July 2015 and May 2016.</p> <p><strong>Results:</strong> In line with observations from the Americas and elsewhere, the single-wave Cabo Verdean ZIKV epidemic was characterized by a basic reproductive number of 1.85 (95% CI, 1.5 – 2.2), with overall the attack rate of 51.1% (range 42.1 – 61.1) and observation rate of 2.7% (range 2.29 – 3.33).</p> <p><strong>Conclusion:</strong> Current herd-immunity may not be sufficient to prevent future small-to-medium epidemics in Cabo Verde. Together with a small observation rate, these results highlight the need for rapid and integrated epidemiological, molecular and genomic surveillance to tackle forthcoming outbreaks of ZIKV and other arboviruses.</p>
spellingShingle Lourenço, J
de Lourdes Monteiro, M
Valdez, Y
Monteiro Rodrigues, J
Pybus, O
Rodrigues Faria, N
Epidemiology of the Zika virus outbreak in the Cabo Verde Islands, West Africa
title Epidemiology of the Zika virus outbreak in the Cabo Verde Islands, West Africa
title_full Epidemiology of the Zika virus outbreak in the Cabo Verde Islands, West Africa
title_fullStr Epidemiology of the Zika virus outbreak in the Cabo Verde Islands, West Africa
title_full_unstemmed Epidemiology of the Zika virus outbreak in the Cabo Verde Islands, West Africa
title_short Epidemiology of the Zika virus outbreak in the Cabo Verde Islands, West Africa
title_sort epidemiology of the zika virus outbreak in the cabo verde islands west africa
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