The α-globin super-enhancer acts in an orientation-dependent manner

The α-globin super-enhancer acts in an orientation-dependent manner

Individual enhancers are defined as short genomic regulatory elements, bound by transcription factors, and able to activate cell-specific gene expression at a distance, in an orientation-independent manner. Within mammalian genomes, enhancer-like elements may be found individually or within clusters...

Podrobná bibliografie
Hlavní autoři:	Kassouf, MT, Francis, HS, Gosden, M, Suciu, MC, Downes, DJ, Harrold, C, Larke, M, Oudelaar, M, Cornell, L, Blayney, J, Telenius, J, Xella, B, Shen, Y, Sousos, N, Sharpe, JA, Sloane-Stanley, J, Smith, AJH, Babbs, C, Hughes, JR, Higgs, DR
Médium:	Journal article
Jazyk:	English
Vydáno:	Nature Research 2025

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