Localized pmrB hypermutation drives the evolution of colistin heteroresistance
Colistin has emerged as an important last line of defence for the treatment of infections caused by antibiotic resistant Gram-negative pathogens, but colistin resistance remains poorly understood. Here we investigate the responses of |1,000 populations of an MDR strain of P. aeruginosa to a high dos...
| Hlavní autoři: | , , |
|---|---|
| Médium: | Journal article |
| Jazyk: | English |
| Vydáno: |
Cell Press
2022
|