The role of transcription and RNA/DNA structures in the pathology of Huntington's disease
<p>Huntington’s Disease (HD) is a repeat expansion disease where a CAG-triplet expansion in the first exon 1 of the huntingtin (<em>HTT</em>) gene leads to the production of a mutant HTT (mHTT) protein. mHTT forms toxic aggregates that alter mitochondrial function, impair protein d...
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| Format: | Thesis |
| Language: | English |
| Published: |
2023
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