Molecular analysis of phyllodes tumors reveals distinct changes in the epithelial and stromal components.

Phyllodes tumors are fibroepithelial mammary lesions that tend to behave in a benign fashion but may undergo sarcomatous transformation. A study of clonality in these tumors has suggested that the epithelial component is polyclonal, but the stroma is monoclonal, and thus forms the neoplastic compone...

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Bibliographic Details
Main Authors: Sawyer, E, Hanby, A, Ellis, P, Lakhani, SR, Ellis, I, Boyle, S, Tomlinson, I
Format: Journal article
Language:English
Published: 2000