Molecular analysis of phyllodes tumors reveals distinct changes in the epithelial and stromal components.
Phyllodes tumors are fibroepithelial mammary lesions that tend to behave in a benign fashion but may undergo sarcomatous transformation. A study of clonality in these tumors has suggested that the epithelial component is polyclonal, but the stroma is monoclonal, and thus forms the neoplastic compone...
Main Authors: | Sawyer, E, Hanby, A, Ellis, P, Lakhani, SR, Ellis, I, Boyle, S, Tomlinson, I |
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Format: | Journal article |
Language: | English |
Published: |
2000
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