Maternal anti-D concentrations and outcome in rhesus haemolytic disease of the newborn.
The relation between maternal anti-D concentrations, measured against the British working standard, and outcome of rhesus-sensitised pregnancies was studied. There is a clear relation between increasing anti-D concentrations and the chance of a severely affected baby. Of those pregnancies (78) where...
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
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1982
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| _version_ | 1797053942729801728 |
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| author | Bowell, P Wainscoat, J Peto, T Gunson, H |
| author_facet | Bowell, P Wainscoat, J Peto, T Gunson, H |
| author_sort | Bowell, P |
| collection | OXFORD |
| description | The relation between maternal anti-D concentrations, measured against the British working standard, and outcome of rhesus-sensitised pregnancies was studied. There is a clear relation between increasing anti-D concentrations and the chance of a severely affected baby. Of those pregnancies (78) where serial anti-D concentrations remained below 4 IU/ml, no baby had a cord haemoglobin below 10 g/dl and three had exchange transfusions. In contrast, of those mothers (106) with anti-D concentrations above 4 IU/ml, 23 had babies with a cord haemoglobin below 10 g/dl and 79 babies had exchange transfusions. It is suggested that those pregnancies where anti-D concentrations remain below 4 IU/ml represent a relatively safe group in which amniocentesis may be avoided. |
| first_indexed | 2024-03-06T18:50:39Z |
| format | Journal article |
| id | oxford-uuid:1019819f-b8d7-4830-ae60-92611ecf9688 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T18:50:39Z |
| publishDate | 1982 |
| record_format | dspace |
| spelling | oxford-uuid:1019819f-b8d7-4830-ae60-92611ecf96882022-03-26T09:54:40ZMaternal anti-D concentrations and outcome in rhesus haemolytic disease of the newborn.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:1019819f-b8d7-4830-ae60-92611ecf9688EnglishSymplectic Elements at Oxford1982Bowell, PWainscoat, JPeto, TGunson, HThe relation between maternal anti-D concentrations, measured against the British working standard, and outcome of rhesus-sensitised pregnancies was studied. There is a clear relation between increasing anti-D concentrations and the chance of a severely affected baby. Of those pregnancies (78) where serial anti-D concentrations remained below 4 IU/ml, no baby had a cord haemoglobin below 10 g/dl and three had exchange transfusions. In contrast, of those mothers (106) with anti-D concentrations above 4 IU/ml, 23 had babies with a cord haemoglobin below 10 g/dl and 79 babies had exchange transfusions. It is suggested that those pregnancies where anti-D concentrations remain below 4 IU/ml represent a relatively safe group in which amniocentesis may be avoided. |
| spellingShingle | Bowell, P Wainscoat, J Peto, T Gunson, H Maternal anti-D concentrations and outcome in rhesus haemolytic disease of the newborn. |
| title | Maternal anti-D concentrations and outcome in rhesus haemolytic disease of the newborn. |
| title_full | Maternal anti-D concentrations and outcome in rhesus haemolytic disease of the newborn. |
| title_fullStr | Maternal anti-D concentrations and outcome in rhesus haemolytic disease of the newborn. |
| title_full_unstemmed | Maternal anti-D concentrations and outcome in rhesus haemolytic disease of the newborn. |
| title_short | Maternal anti-D concentrations and outcome in rhesus haemolytic disease of the newborn. |
| title_sort | maternal anti d concentrations and outcome in rhesus haemolytic disease of the newborn |
| work_keys_str_mv | AT bowellp maternalantidconcentrationsandoutcomeinrhesushaemolyticdiseaseofthenewborn AT wainscoatj maternalantidconcentrationsandoutcomeinrhesushaemolyticdiseaseofthenewborn AT petot maternalantidconcentrationsandoutcomeinrhesushaemolyticdiseaseofthenewborn AT gunsonh maternalantidconcentrationsandoutcomeinrhesushaemolyticdiseaseofthenewborn |