Liquidity in immune cell signaling
Signaling molecules (blue) form liquid-like phases, instead of static aggregates, in a reconstituted system using an artificial lipid bilayer. Shown is a model of clustered pLAT and associated signaling molecules that phase separate into a liquid-like droplet in response to TCR activation. The clust...
| Huvudupphovsmän: | , |
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| Materialtyp: | Journal article |
| Språk: | English |
| Publicerad: |
American Association for the Advancement of Science
2016
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| _version_ | 1826259502841724928 |
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| author | Dustin, M Muller, J |
| author_facet | Dustin, M Muller, J |
| author_sort | Dustin, M |
| collection | OXFORD |
| description | Signaling molecules (blue) form liquid-like phases, instead of static aggregates, in a reconstituted system using an artificial lipid bilayer. Shown is a model of clustered pLAT and associated signaling molecules that phase separate into a liquid-like droplet in response to TCR activation. The cluster induces actin polymerization, which is a solid phase gel that changes the shape of the liquid-like droplet. |
| first_indexed | 2024-03-06T18:50:55Z |
| format | Journal article |
| id | oxford-uuid:102cf542-f93e-4bb9-83b1-9fc8f2aa0c9a |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T18:50:55Z |
| publishDate | 2016 |
| publisher | American Association for the Advancement of Science |
| record_format | dspace |
| spelling | oxford-uuid:102cf542-f93e-4bb9-83b1-9fc8f2aa0c9a2022-03-26T09:55:06ZLiquidity in immune cell signalingJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:102cf542-f93e-4bb9-83b1-9fc8f2aa0c9aEnglishSymplectic Elements at OxfordAmerican Association for the Advancement of Science2016Dustin, MMuller, JSignaling molecules (blue) form liquid-like phases, instead of static aggregates, in a reconstituted system using an artificial lipid bilayer. Shown is a model of clustered pLAT and associated signaling molecules that phase separate into a liquid-like droplet in response to TCR activation. The cluster induces actin polymerization, which is a solid phase gel that changes the shape of the liquid-like droplet. |
| spellingShingle | Dustin, M Muller, J Liquidity in immune cell signaling |
| title | Liquidity in immune cell signaling |
| title_full | Liquidity in immune cell signaling |
| title_fullStr | Liquidity in immune cell signaling |
| title_full_unstemmed | Liquidity in immune cell signaling |
| title_short | Liquidity in immune cell signaling |
| title_sort | liquidity in immune cell signaling |
| work_keys_str_mv | AT dustinm liquidityinimmunecellsignaling AT mullerj liquidityinimmunecellsignaling |