Spatial and subcellular gene expression patterns in myogenic differentiation and muscle pathology

<p>Duchenne muscular dystrophy (DMD) is a debilitating muscle-wasting disorder caused by lack of dystrophin protein. Promising dystrophin-restoration therapies such as gene editing using the CRISPR-Cas9 system and antisense oligonucleotide-mediated exon skipping using peptide-phosphorodiamidat...