Rapid, comprehensive, and affordable mycobacterial diagnosis with whole-genome sequencing: a prospective study

Rapid, comprehensive, and affordable mycobacterial diagnosis with whole-genome sequencing: a prospective study

Slow and cumbersome laboratory diagnostics for Mycobacterium tuberculosis complex (MTBC) risk delayed treatment and poor patient outcomes. Whole-genome sequencing (WGS) could potentially provide a rapid and comprehensive diagnostic solution. In this prospective study, we compare real-time WGS with r...

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Bibliographic Details
Main Authors: Pankhurst, L, Fermont, J, del Ojo Elias, C, Votintseva, A, Walker, T, Cole, K, Davies, J, Gascoyne-Binzi, D, Kohl, T, Kong, C, Lemaitre, N, Niemann, S, Paul, J, Rogers, T, Roycroft, E, Smith, E, Supply, P, Tang, P, Wilcox, M
Format: Journal article
Published: Lancet 2015
Description
Summary:Slow and cumbersome laboratory diagnostics for Mycobacterium tuberculosis complex (MTBC) risk delayed treatment and poor patient outcomes. Whole-genome sequencing (WGS) could potentially provide a rapid and comprehensive diagnostic solution. In this prospective study, we compare real-time WGS with routine MTBC diagnostic workflows.

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