Rapid, comprehensive, and affordable mycobacterial diagnosis with whole-genome sequencing: a prospective study

Slow and cumbersome laboratory diagnostics for Mycobacterium tuberculosis complex (MTBC) risk delayed treatment and poor patient outcomes. Whole-genome sequencing (WGS) could potentially provide a rapid and comprehensive diagnostic solution. In this prospective study, we compare real-time WGS with r...

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Main Authors: Pankhurst, L, Fermont, J, del Ojo Elias, C, Votintseva, A, Walker, T, Cole, K, Davies, J, Gascoyne-Binzi, D, Kohl, T, Kong, C, Lemaitre, N, Niemann, S, Paul, J, Rogers, T, Roycroft, E, Smith, E, Supply, P, Tang, P, Wilcox, M
Format: Journal article
Published: Lancet 2015
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author Pankhurst, L
Fermont, J
del Ojo Elias, C
Votintseva, A
Walker, T
Cole, K
Davies, J
Gascoyne-Binzi, D
Kohl, T
Kong, C
Lemaitre, N
Niemann, S
Paul, J
Rogers, T
Roycroft, E
Smith, E
Supply, P
Tang, P
Wilcox, M
author_facet Pankhurst, L
Fermont, J
del Ojo Elias, C
Votintseva, A
Walker, T
Cole, K
Davies, J
Gascoyne-Binzi, D
Kohl, T
Kong, C
Lemaitre, N
Niemann, S
Paul, J
Rogers, T
Roycroft, E
Smith, E
Supply, P
Tang, P
Wilcox, M
author_sort Pankhurst, L
collection OXFORD
description Slow and cumbersome laboratory diagnostics for Mycobacterium tuberculosis complex (MTBC) risk delayed treatment and poor patient outcomes. Whole-genome sequencing (WGS) could potentially provide a rapid and comprehensive diagnostic solution. In this prospective study, we compare real-time WGS with routine MTBC diagnostic workflows.
first_indexed 2024-03-06T18:51:12Z
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spelling oxford-uuid:1048dd74-0c12-4c60-99a3-bf7ac3e567d82022-03-26T09:55:40ZRapid, comprehensive, and affordable mycobacterial diagnosis with whole-genome sequencing: a prospective studyJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:1048dd74-0c12-4c60-99a3-bf7ac3e567d8Symplectic Elements at OxfordLancet2015Pankhurst, LFermont, Jdel Ojo Elias, CVotintseva, AWalker, TCole, KDavies, JGascoyne-Binzi, DKohl, TKong, CLemaitre, NNiemann, SPaul, JRogers, TRoycroft, ESmith, ESupply, PTang, PWilcox, MSlow and cumbersome laboratory diagnostics for Mycobacterium tuberculosis complex (MTBC) risk delayed treatment and poor patient outcomes. Whole-genome sequencing (WGS) could potentially provide a rapid and comprehensive diagnostic solution. In this prospective study, we compare real-time WGS with routine MTBC diagnostic workflows.
spellingShingle Pankhurst, L
Fermont, J
del Ojo Elias, C
Votintseva, A
Walker, T
Cole, K
Davies, J
Gascoyne-Binzi, D
Kohl, T
Kong, C
Lemaitre, N
Niemann, S
Paul, J
Rogers, T
Roycroft, E
Smith, E
Supply, P
Tang, P
Wilcox, M
Rapid, comprehensive, and affordable mycobacterial diagnosis with whole-genome sequencing: a prospective study
title Rapid, comprehensive, and affordable mycobacterial diagnosis with whole-genome sequencing: a prospective study
title_full Rapid, comprehensive, and affordable mycobacterial diagnosis with whole-genome sequencing: a prospective study
title_fullStr Rapid, comprehensive, and affordable mycobacterial diagnosis with whole-genome sequencing: a prospective study
title_full_unstemmed Rapid, comprehensive, and affordable mycobacterial diagnosis with whole-genome sequencing: a prospective study
title_short Rapid, comprehensive, and affordable mycobacterial diagnosis with whole-genome sequencing: a prospective study
title_sort rapid comprehensive and affordable mycobacterial diagnosis with whole genome sequencing a prospective study
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