Brain tumour segmentation using a triplanar ensemble of U-Nets on MR images

Gliomas appear with wide variation in their characteristics both in terms of their appearance and location on brain MR images, which makes robust tumour segmentation highly challenging, and leads to high inter-rater variability even in manual segmentations. In this work, we propose a triplanar ensem...

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Bibliographic Details
Main Authors: Sundaresan, V, Griffanti, L, Jenkinson, M
Format: Book section
Language:English
Published: Springer 2021
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author Sundaresan, V
Griffanti, L
Jenkinson, M
author_facet Sundaresan, V
Griffanti, L
Jenkinson, M
author_sort Sundaresan, V
collection OXFORD
description Gliomas appear with wide variation in their characteristics both in terms of their appearance and location on brain MR images, which makes robust tumour segmentation highly challenging, and leads to high inter-rater variability even in manual segmentations. In this work, we propose a triplanar ensemble network, with an independent tumour core prediction module, for accurate segmentation of these tumours and their sub-regions. On evaluating our method on the MICCAI Brain Tumor Segmentation (BraTS) challenge validation dataset, for tumour sub-regions, we achieved a Dice similarity coefficient of 0.77 for both enhancing tumour (ET) and tumour core (TC). In the case of the whole tumour (WT) region, we achieved a Dice value of 0.89, which is on par with the top-ranking methods from BraTS’17-19. Our method achieved an evaluation score that was the equal 5th highest value (with our method ranking in 10th place) in the BraTS’20 challenge, with mean Dice values of 0.81, 0.89 and 0.84 on ET, WT and TC regions respectively on the BraTS’20 unseen test dataset.
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spelling oxford-uuid:10694183-af1a-4010-ac19-4fc7d96914272022-03-26T09:56:13ZBrain tumour segmentation using a triplanar ensemble of U-Nets on MR imagesBook sectionhttp://purl.org/coar/resource_type/c_1843uuid:10694183-af1a-4010-ac19-4fc7d9691427EnglishSymplectic ElementsSpringer2021Sundaresan, VGriffanti, LJenkinson, MGliomas appear with wide variation in their characteristics both in terms of their appearance and location on brain MR images, which makes robust tumour segmentation highly challenging, and leads to high inter-rater variability even in manual segmentations. In this work, we propose a triplanar ensemble network, with an independent tumour core prediction module, for accurate segmentation of these tumours and their sub-regions. On evaluating our method on the MICCAI Brain Tumor Segmentation (BraTS) challenge validation dataset, for tumour sub-regions, we achieved a Dice similarity coefficient of 0.77 for both enhancing tumour (ET) and tumour core (TC). In the case of the whole tumour (WT) region, we achieved a Dice value of 0.89, which is on par with the top-ranking methods from BraTS’17-19. Our method achieved an evaluation score that was the equal 5th highest value (with our method ranking in 10th place) in the BraTS’20 challenge, with mean Dice values of 0.81, 0.89 and 0.84 on ET, WT and TC regions respectively on the BraTS’20 unseen test dataset.
spellingShingle Sundaresan, V
Griffanti, L
Jenkinson, M
Brain tumour segmentation using a triplanar ensemble of U-Nets on MR images
title Brain tumour segmentation using a triplanar ensemble of U-Nets on MR images
title_full Brain tumour segmentation using a triplanar ensemble of U-Nets on MR images
title_fullStr Brain tumour segmentation using a triplanar ensemble of U-Nets on MR images
title_full_unstemmed Brain tumour segmentation using a triplanar ensemble of U-Nets on MR images
title_short Brain tumour segmentation using a triplanar ensemble of U-Nets on MR images
title_sort brain tumour segmentation using a triplanar ensemble of u nets on mr images
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AT jenkinsonm braintumoursegmentationusingatriplanarensembleofunetsonmrimages