Elimination of a bacterial pore-forming toxin by sequential endocytosis and exocytosis.

Elimination of a bacterial pore-forming toxin by sequential endocytosis and exocytosis.

Staphylococcus aureus alpha-toxin is the archetype of bacterial pore forming toxins and a key virulence factor secreted by the majority of clinical isolates of S. aureus. Toxin monomers bind to target cells and oligomerize to form small beta-barrel pores in the plasma membrane. Many nucleated cells...

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Bibliografische gegevens
Hoofdauteurs:	Husmann, M, Beckmann, E, Boller, K, Kloft, N, Tenzer, S, Bobkiewicz, W, Neukirch, C, Bayley, H, Bhakdi, S
Formaat:	Journal article
Taal:	English
Gepubliceerd in:	2009

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