The emergence of enterovirus D68 in England in autumn 2014 and the necessity for reinforcing enterovirus respiratory screening
In autumn 2014, enterovirus D68 (EV-D68) cases presenting with severe respiratory or neurological disease were described in countries worldwide. To describe the epidemiology and virological characteristics of EV-D68 in England, we collected clinical information on laboratory-confirmed EV-D68 cases d...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
Cambridge University Press
2017
|
| _version_ | 1797054014881267712 |
|---|---|
| author | Carrion Martin, A Pebody, R Danis, K Ellis, J Niazi, S De Lusignan, S Brown, K Zambon, M Allen, D |
| author_facet | Carrion Martin, A Pebody, R Danis, K Ellis, J Niazi, S De Lusignan, S Brown, K Zambon, M Allen, D |
| author_sort | Carrion Martin, A |
| collection | OXFORD |
| description | In autumn 2014, enterovirus D68 (EV-D68) cases presenting with severe respiratory or neurological disease were described in countries worldwide. To describe the epidemiology and virological characteristics of EV-D68 in England, we collected clinical information on laboratory-confirmed EV-D68 cases detected in secondary care (hospitals), between September 2014 and January 2015. In primary care (general practitioners), respiratory swabs collected (September 2013-January 2015) from patients presenting with influenza-like illness were tested for EV-D68. In secondary care 55 EV-D68 cases were detected. Among those, 45 cases had clinical information available and 89% (40/45) presented with severe respiratory symptoms. Detection of EV-D68 among patients in primary care increased from 0.4% (4/1074; 95% CI 0.1-1.0) (September 2013-January 2014) to 0.8% (11/1359; 95% CI 0.4-1.5) (September 2014-January 2015). Characterization of EV-D68 strains circulating in England since 2012 and up to winter 2014/2015 indicated that those strains were genetically similar to those detected in 2014 in USA. We recommend reinforcing enterovirus surveillance through screening respiratory samples of suspected cases. |
| first_indexed | 2024-03-06T18:51:36Z |
| format | Journal article |
| id | oxford-uuid:106defa8-53f6-4501-96f8-b78479f40a2c |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T18:51:36Z |
| publishDate | 2017 |
| publisher | Cambridge University Press |
| record_format | dspace |
| spelling | oxford-uuid:106defa8-53f6-4501-96f8-b78479f40a2c2022-03-26T09:56:30ZThe emergence of enterovirus D68 in England in autumn 2014 and the necessity for reinforcing enterovirus respiratory screeningJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:106defa8-53f6-4501-96f8-b78479f40a2cEnglishSymplectic Elements at OxfordCambridge University Press2017Carrion Martin, APebody, RDanis, KEllis, JNiazi, SDe Lusignan, SBrown, KZambon, MAllen, DIn autumn 2014, enterovirus D68 (EV-D68) cases presenting with severe respiratory or neurological disease were described in countries worldwide. To describe the epidemiology and virological characteristics of EV-D68 in England, we collected clinical information on laboratory-confirmed EV-D68 cases detected in secondary care (hospitals), between September 2014 and January 2015. In primary care (general practitioners), respiratory swabs collected (September 2013-January 2015) from patients presenting with influenza-like illness were tested for EV-D68. In secondary care 55 EV-D68 cases were detected. Among those, 45 cases had clinical information available and 89% (40/45) presented with severe respiratory symptoms. Detection of EV-D68 among patients in primary care increased from 0.4% (4/1074; 95% CI 0.1-1.0) (September 2013-January 2014) to 0.8% (11/1359; 95% CI 0.4-1.5) (September 2014-January 2015). Characterization of EV-D68 strains circulating in England since 2012 and up to winter 2014/2015 indicated that those strains were genetically similar to those detected in 2014 in USA. We recommend reinforcing enterovirus surveillance through screening respiratory samples of suspected cases. |
| spellingShingle | Carrion Martin, A Pebody, R Danis, K Ellis, J Niazi, S De Lusignan, S Brown, K Zambon, M Allen, D The emergence of enterovirus D68 in England in autumn 2014 and the necessity for reinforcing enterovirus respiratory screening |
| title | The emergence of enterovirus D68 in England in autumn 2014 and the necessity for reinforcing enterovirus respiratory screening |
| title_full | The emergence of enterovirus D68 in England in autumn 2014 and the necessity for reinforcing enterovirus respiratory screening |
| title_fullStr | The emergence of enterovirus D68 in England in autumn 2014 and the necessity for reinforcing enterovirus respiratory screening |
| title_full_unstemmed | The emergence of enterovirus D68 in England in autumn 2014 and the necessity for reinforcing enterovirus respiratory screening |
| title_short | The emergence of enterovirus D68 in England in autumn 2014 and the necessity for reinforcing enterovirus respiratory screening |
| title_sort | emergence of enterovirus d68 in england in autumn 2014 and the necessity for reinforcing enterovirus respiratory screening |
| work_keys_str_mv | AT carrionmartina theemergenceofenterovirusd68inenglandinautumn2014andthenecessityforreinforcingenterovirusrespiratoryscreening AT pebodyr theemergenceofenterovirusd68inenglandinautumn2014andthenecessityforreinforcingenterovirusrespiratoryscreening AT danisk theemergenceofenterovirusd68inenglandinautumn2014andthenecessityforreinforcingenterovirusrespiratoryscreening AT ellisj theemergenceofenterovirusd68inenglandinautumn2014andthenecessityforreinforcingenterovirusrespiratoryscreening AT niazis theemergenceofenterovirusd68inenglandinautumn2014andthenecessityforreinforcingenterovirusrespiratoryscreening AT delusignans theemergenceofenterovirusd68inenglandinautumn2014andthenecessityforreinforcingenterovirusrespiratoryscreening AT brownk theemergenceofenterovirusd68inenglandinautumn2014andthenecessityforreinforcingenterovirusrespiratoryscreening AT zambonm theemergenceofenterovirusd68inenglandinautumn2014andthenecessityforreinforcingenterovirusrespiratoryscreening AT allend theemergenceofenterovirusd68inenglandinautumn2014andthenecessityforreinforcingenterovirusrespiratoryscreening AT carrionmartina emergenceofenterovirusd68inenglandinautumn2014andthenecessityforreinforcingenterovirusrespiratoryscreening AT pebodyr emergenceofenterovirusd68inenglandinautumn2014andthenecessityforreinforcingenterovirusrespiratoryscreening AT danisk emergenceofenterovirusd68inenglandinautumn2014andthenecessityforreinforcingenterovirusrespiratoryscreening AT ellisj emergenceofenterovirusd68inenglandinautumn2014andthenecessityforreinforcingenterovirusrespiratoryscreening AT niazis emergenceofenterovirusd68inenglandinautumn2014andthenecessityforreinforcingenterovirusrespiratoryscreening AT delusignans emergenceofenterovirusd68inenglandinautumn2014andthenecessityforreinforcingenterovirusrespiratoryscreening AT brownk emergenceofenterovirusd68inenglandinautumn2014andthenecessityforreinforcingenterovirusrespiratoryscreening AT zambonm emergenceofenterovirusd68inenglandinautumn2014andthenecessityforreinforcingenterovirusrespiratoryscreening AT allend emergenceofenterovirusd68inenglandinautumn2014andthenecessityforreinforcingenterovirusrespiratoryscreening |