TSG-6 binds via its CUB_C domain to the cell-binding domain of fibronectin and increases fibronectin matrix assembly.

TSG-6 binds via its CUB_C domain to the cell-binding domain of fibronectin and increases fibronectin matrix assembly.

Human plasma fibronectin binds with high affinity to the inflammation-induced secreted protein TSG-6. Fibronectin binds to the CUB_C domain of TSG-6 but not to its Link module. TSG-6 can thus act as a bridging molecule to facilitate fibronectin association with the TSG-6 Link module ligand thrombosp...

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Bibliographic Details
Main Authors:	Kuznetsova, SA, Mahoney, D, Martin-Manso, G, Ali, T, Nentwich, H, Sipes, J, Zeng, B, Vogel, T, Day, A, Roberts, D
Format:	Journal article
Language:	English
Published:	2008

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