Humoral immune responses to adenovirus vectors in the brain.
We have investigated the humoral immune response to E1-deleted adenovirus vectors encoding the lacZ gene introduced into the brains of mice. Injection of these non-replicating vectors into the brain induced systemic antibody production to adenovirus vectors in dose dependent manner. Apparent antibod...
Main Authors: | Kajiwara, K, Byrnes, A, Ohmoto, Y, Charlton, H, Wood, M, Wood, K |
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Format: | Journal article |
Language: | English |
Published: |
2000
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