Humoral immune responses to adenovirus vectors in the brain.

We have investigated the humoral immune response to E1-deleted adenovirus vectors encoding the lacZ gene introduced into the brains of mice. Injection of these non-replicating vectors into the brain induced systemic antibody production to adenovirus vectors in dose dependent manner. Apparent antibod...

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Détails bibliographiques
Auteurs principaux: Kajiwara, K, Byrnes, A, Ohmoto, Y, Charlton, H, Wood, M, Wood, K
Format: Journal article
Langue:English
Publié: 2000