Evolving management of patients treated by drug-eluting stent: Prevention of late events

Summary: Drug eluting stents (DES) were introduced in clinical practice to overcome the problem of in-stent restenosis (ISR) that limited the overall efficacy of percutaneous coronary revascularization with bare metal stent (BMS). Long-term outcome data confirm a sustained benefit of DES as compared...

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Bibliographic Details
Main Authors: Niccoli, G, Sgueglia, G, Montone, R, Roberto, M, Banning, A, Crea, F
Format: Journal article
Language:English
Published: Elsevier 2014
Description
Summary:Summary: Drug eluting stents (DES) were introduced in clinical practice to overcome the problem of in-stent restenosis (ISR) that limited the overall efficacy of percutaneous coronary revascularization with bare metal stent (BMS). Long-term outcome data confirm a sustained benefit of DES as compared with BMS. However, this benefit is mainly evident in the first year of follow-up. Indeed, DES-related events may extend over this time, due to late events (late ISR and/or very late stent thrombosis). Prevention of late failure of DES may become a specific therapeutic target. © 2014 Elsevier Inc.