Safety and feasibility of ultrasound-triggered targeted drug delivery of doxorubicin from thermosensitive liposomes in liver tumours (TARDOX): a single-centre, open-label, phase 1 trial

Previous preclinical research has shown that extracorporeal devices can be used to enhance the delivery and distribution of systemically administered anticancer drugs, resulting in increased intratumoural concentrations. We aimed to assess the safety and feasibility of targeted release and enhanced...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Lyon, PC, Gray, MD, Mannaris, C, Folkes, LK, Stratford, M, Campo, L, Chung, DYF, Scott, S, Anderson, M, Goldin, R, Carlisle, R, Wu, F, Middleton, MR, Gleeson, FV, Coussios, CC
Format: Journal article
Sprache:English
Veröffentlicht: Elsevier 2018