Markedly elevated CA19-9 associated with benign ovarian cyst and ascites.
A 60-year-old woman presented after a fall and was noted to have ascites. She had a history of ulcerative colitis. History and physical examination did not reveal the likely aetiology of the ascites, but a sample showed it to be a blood-stained exudate. A malignant cause appeared likely, cross-secti...
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2009
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| _version_ | 1826259768049664000 |
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| author | Brain, O Brown, L Suvarna, S Chapman, R |
| author_facet | Brain, O Brown, L Suvarna, S Chapman, R |
| author_sort | Brain, O |
| collection | OXFORD |
| description | A 60-year-old woman presented after a fall and was noted to have ascites. She had a history of ulcerative colitis. History and physical examination did not reveal the likely aetiology of the ascites, but a sample showed it to be a blood-stained exudate. A malignant cause appeared likely, cross-sectional imaging was arranged and tumour markers sent. CA125 was 34 IU/ml (0-30); α-fetoprotein (AFP) and carcinoembryonic antigen (CEA) were normal. However, CA19-9 was 2880 U/ml (0-31). Pancreatic carcinoma or cholangiocarcinoma were of prime concern, but a CT scan and MRI imaging were normal. At laparoscopy a benign ruptured ovarian cyst was detected, and ascites drained. CA19-9 returned to normal and the patient remains well 9 months later. This case demonstrates how tumour markers may be misleading in the context of diagnostics, and is the highest reported example of CA19-9 rise in the context of benign ascites and benign ovarian pathology. |
| first_indexed | 2024-03-06T18:54:59Z |
| format | Journal article |
| id | oxford-uuid:1188be75-5972-4ff8-9ad9-9d16fbda721f |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T18:54:59Z |
| publishDate | 2009 |
| record_format | dspace |
| spelling | oxford-uuid:1188be75-5972-4ff8-9ad9-9d16fbda721f2022-03-26T10:02:48ZMarkedly elevated CA19-9 associated with benign ovarian cyst and ascites.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:1188be75-5972-4ff8-9ad9-9d16fbda721fEnglishSymplectic Elements at Oxford2009Brain, OBrown, LSuvarna, SChapman, RA 60-year-old woman presented after a fall and was noted to have ascites. She had a history of ulcerative colitis. History and physical examination did not reveal the likely aetiology of the ascites, but a sample showed it to be a blood-stained exudate. A malignant cause appeared likely, cross-sectional imaging was arranged and tumour markers sent. CA125 was 34 IU/ml (0-30); α-fetoprotein (AFP) and carcinoembryonic antigen (CEA) were normal. However, CA19-9 was 2880 U/ml (0-31). Pancreatic carcinoma or cholangiocarcinoma were of prime concern, but a CT scan and MRI imaging were normal. At laparoscopy a benign ruptured ovarian cyst was detected, and ascites drained. CA19-9 returned to normal and the patient remains well 9 months later. This case demonstrates how tumour markers may be misleading in the context of diagnostics, and is the highest reported example of CA19-9 rise in the context of benign ascites and benign ovarian pathology. |
| spellingShingle | Brain, O Brown, L Suvarna, S Chapman, R Markedly elevated CA19-9 associated with benign ovarian cyst and ascites. |
| title | Markedly elevated CA19-9 associated with benign ovarian cyst and ascites. |
| title_full | Markedly elevated CA19-9 associated with benign ovarian cyst and ascites. |
| title_fullStr | Markedly elevated CA19-9 associated with benign ovarian cyst and ascites. |
| title_full_unstemmed | Markedly elevated CA19-9 associated with benign ovarian cyst and ascites. |
| title_short | Markedly elevated CA19-9 associated with benign ovarian cyst and ascites. |
| title_sort | markedly elevated ca19 9 associated with benign ovarian cyst and ascites |
| work_keys_str_mv | AT braino markedlyelevatedca199associatedwithbenignovariancystandascites AT brownl markedlyelevatedca199associatedwithbenignovariancystandascites AT suvarnas markedlyelevatedca199associatedwithbenignovariancystandascites AT chapmanr markedlyelevatedca199associatedwithbenignovariancystandascites |