Emerging challenges in regulatory T cell function and biology.
Much progress has been made in understanding how the immune system is regulated, with a great deal of recent interest in naturally occurring CD4+ regulatory T cells that actively engage in the maintenance of immunological self-tolerance and immune homeostasis. The challenge ahead for immunologists i...
| Váldodahkkit: | , |
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| Materiálatiipa: | Journal article |
| Giella: | English |
| Almmustuhtton: |
2007
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| _version_ | 1826259797755822080 |
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| author | Sakaguchi, S Powrie, F |
| author_facet | Sakaguchi, S Powrie, F |
| author_sort | Sakaguchi, S |
| collection | OXFORD |
| description | Much progress has been made in understanding how the immune system is regulated, with a great deal of recent interest in naturally occurring CD4+ regulatory T cells that actively engage in the maintenance of immunological self-tolerance and immune homeostasis. The challenge ahead for immunologists is the further elucidation of the molecular and cellular processes that govern the development and function of these cells. From this, exciting possibilities are emerging for the manipulation of regulatory T cell pathways in treating immunological diseases and suppressing or augmenting physiological immune responses. |
| first_indexed | 2024-03-06T18:55:28Z |
| format | Journal article |
| id | oxford-uuid:11aeca6b-e740-4d7f-a331-3b240928e81b |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T18:55:28Z |
| publishDate | 2007 |
| record_format | dspace |
| spelling | oxford-uuid:11aeca6b-e740-4d7f-a331-3b240928e81b2022-03-26T10:03:40ZEmerging challenges in regulatory T cell function and biology.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:11aeca6b-e740-4d7f-a331-3b240928e81bEnglishSymplectic Elements at Oxford2007Sakaguchi, SPowrie, FMuch progress has been made in understanding how the immune system is regulated, with a great deal of recent interest in naturally occurring CD4+ regulatory T cells that actively engage in the maintenance of immunological self-tolerance and immune homeostasis. The challenge ahead for immunologists is the further elucidation of the molecular and cellular processes that govern the development and function of these cells. From this, exciting possibilities are emerging for the manipulation of regulatory T cell pathways in treating immunological diseases and suppressing or augmenting physiological immune responses. |
| spellingShingle | Sakaguchi, S Powrie, F Emerging challenges in regulatory T cell function and biology. |
| title | Emerging challenges in regulatory T cell function and biology. |
| title_full | Emerging challenges in regulatory T cell function and biology. |
| title_fullStr | Emerging challenges in regulatory T cell function and biology. |
| title_full_unstemmed | Emerging challenges in regulatory T cell function and biology. |
| title_short | Emerging challenges in regulatory T cell function and biology. |
| title_sort | emerging challenges in regulatory t cell function and biology |
| work_keys_str_mv | AT sakaguchis emergingchallengesinregulatorytcellfunctionandbiology AT powrief emergingchallengesinregulatorytcellfunctionandbiology |