Genome-wide association meta-analyses combining multiple risk phenotypes provide insights into the genetic architecture of cutaneous melanoma susceptibility

Most genetic susceptibility to cutaneous melanoma remains to be discovered. Meta-analysis genome-wide association study (GWAS) of 36,760 cases of melanoma (67% newly genotyped) and 375,188 controls identified 54 significant (P < 5 × 10−8) loci with 68 independent single nucleotide polymorphisms....

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Bibliografiske detaljer
Main Authors: Landi, MT, Bishop, DT, MacGregor, S, Hunter, D
Format: Journal article
Sprog:English
Udgivet: Springer Nature 2020