Dopamine oxidation at gold electrodes: mechanism and kinetics near neutral pH
The two-electron electrochemical oxidation of dopamine is studied voltammetrically at gold macroelectrodes around neutral pH with simulations used to give kinetic and mechanistic data. In particular, the system shows "potential inversion" in which the thermodynamic oxidation potential of d...
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
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Royal Society of Chemistry
2019
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| _version_ | 1797054339859087360 |
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| author | Bacil, R Chen, L Serrano, S Compton, R |
| author_facet | Bacil, R Chen, L Serrano, S Compton, R |
| author_sort | Bacil, R |
| collection | OXFORD |
| description | The two-electron electrochemical oxidation of dopamine is studied voltammetrically at gold macroelectrodes around neutral pH with simulations used to give kinetic and mechanistic data. In particular, the system shows "potential inversion" in which the thermodynamic oxidation potential of dopamine to form the corresponding semi-quinone formation occurs at a more positive potential than that of the oxidation of the semi-quinone to the quinone form. The use of Tafel slopes measured from the voltammograms as a function of the voltage scan rate is show to be a particularly sensitive indicator of mechanism showing the effect of the follow-up chemistry in which the two-electron oxidation product undergoes an irreversible cyclization reaction. |
| first_indexed | 2024-03-06T18:55:53Z |
| format | Journal article |
| id | oxford-uuid:11d17b1c-c56e-49bf-9927-47f4d720e35f |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T18:55:53Z |
| publishDate | 2019 |
| publisher | Royal Society of Chemistry |
| record_format | dspace |
| spelling | oxford-uuid:11d17b1c-c56e-49bf-9927-47f4d720e35f2022-03-26T10:04:24ZDopamine oxidation at gold electrodes: mechanism and kinetics near neutral pHJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:11d17b1c-c56e-49bf-9927-47f4d720e35fEnglishSymplectic Elements at OxfordRoyal Society of Chemistry2019Bacil, RChen, LSerrano, SCompton, RThe two-electron electrochemical oxidation of dopamine is studied voltammetrically at gold macroelectrodes around neutral pH with simulations used to give kinetic and mechanistic data. In particular, the system shows "potential inversion" in which the thermodynamic oxidation potential of dopamine to form the corresponding semi-quinone formation occurs at a more positive potential than that of the oxidation of the semi-quinone to the quinone form. The use of Tafel slopes measured from the voltammograms as a function of the voltage scan rate is show to be a particularly sensitive indicator of mechanism showing the effect of the follow-up chemistry in which the two-electron oxidation product undergoes an irreversible cyclization reaction. |
| spellingShingle | Bacil, R Chen, L Serrano, S Compton, R Dopamine oxidation at gold electrodes: mechanism and kinetics near neutral pH |
| title | Dopamine oxidation at gold electrodes: mechanism and kinetics near neutral pH |
| title_full | Dopamine oxidation at gold electrodes: mechanism and kinetics near neutral pH |
| title_fullStr | Dopamine oxidation at gold electrodes: mechanism and kinetics near neutral pH |
| title_full_unstemmed | Dopamine oxidation at gold electrodes: mechanism and kinetics near neutral pH |
| title_short | Dopamine oxidation at gold electrodes: mechanism and kinetics near neutral pH |
| title_sort | dopamine oxidation at gold electrodes mechanism and kinetics near neutral ph |
| work_keys_str_mv | AT bacilr dopamineoxidationatgoldelectrodesmechanismandkineticsnearneutralph AT chenl dopamineoxidationatgoldelectrodesmechanismandkineticsnearneutralph AT serranos dopamineoxidationatgoldelectrodesmechanismandkineticsnearneutralph AT comptonr dopamineoxidationatgoldelectrodesmechanismandkineticsnearneutralph |