Novel 5 '-utrophin isoforms exhibit species-specific transcriptional profiles and provide additional candidates for therapeutic up-regulation in DMD

Novel 5 '-utrophin isoforms exhibit species-specific transcriptional profiles and provide additional candidates for therapeutic up-regulation in DMD

Bibliografiske detaljer
Main Authors:	Perkins, K, Proudfoot, N, Davies, K
Format:	Conference item
Udgivet:	2012

Lignende værker

Analysis of the transcriptional control of utrophin promoters as a therapeutic strategy for Duchenne muscular dystrophy (DMD).
af: Perkins, K, et al.
Udgivet: (2000)

Second-generation compound for the modulation of utrophin in the therapy of DMD
af: Guiraud, S, et al.
Udgivet: (2015)

Identification of serum protein biomarkers for utrophin based DMD therapy.
af: Guiraud, S, et al.
Udgivet: (2017)

Utrophin upregulation in DMD therapy: current status and new tools for the future
af: Fairclough, R, et al.
Udgivet: (2011)

The role of basal and myogenic factors in the transcriptional activation of utrophin promoter A: implications for therapeutic up-regulation in Duchenne muscular dystrophy.
af: Perkins, K, et al.
Udgivet: (2001)

Embryonic myosin is a regeneration marker to monitor utrophin-based therapies for DMD
af: Guiraud, S, et al.
Udgivet: (2018)

Utrophin up-regulation by an artificial transcription factor in transgenic mice
af: Mattei, E, et al.
Udgivet: (2007)

New orally available compounds which modulate utrophin expression for the therapy of Duchenne muscular dystrophy (DMD)
af: Fairclough, R, et al.
Udgivet: (2014)

The role of utrophin in the potential therapy of Duchenne muscular dystrophy.
af: Perkins, K, et al.
Udgivet: (2002)

Utrophin up-regulation by an artificial transcription factor in transgenic mice.
af: Elisabetta Mattei, et al.
Udgivet: (2007-08-01)

Expression of different isoforms of utrophin in human muscle; potentials for therapy of Duchenne muscular dystrophy
af: Sewry, C, et al.
Udgivet: (2004)

Future clinical and biomarker development for SMTC1100, the first utrophin modulator to enter clinical trials for Duchenne Muscular Dystrophy (DMD)
af: Tinsley, J, et al.
Udgivet: (2013)

A and B utrophin in human muscle and sarcolemmal A-utrophin associated with tumours.
af: Sewry, C, et al.
Udgivet: (2005)

Regulation of utrophin in transgenic mice.
af: Davies, K
Udgivet: (2005)

A-utrophin up-regulation in mdx skeletal muscle is independent of regeneration.
af: Weir, A, et al.
Udgivet: (2004)

Sertoli Cells Improve Myogenic Differentiation, Reduce Fibrogenic Markers, and Induce Utrophin Expression in Human DMD Myoblasts
af: Laura Salvadori, et al.
Udgivet: (2021-10-01)

Up-regulation of utrophin alleviates the dystrophic phenotype in the mdx mouse heart
af: Sang, E, et al.
Udgivet: (2000)

Understanding the endothelial function of utrophin.
af: Ehmsen, J, et al.
Udgivet: (2002)

Ets, Ap-1 and GATA factor families regulate the utrophin B promoter: potential regulatory mechanisms for endothelial-specific expression.
af: Perkins, K, et al.
Udgivet: (2003)

Utrophin luciferase knock-in mouse model for in vivo assessment of drug efficacy in preclinical trials for utrophin upregulation
af: Fairclough, R, et al.
Udgivet: (2010)

Utrophin upregulation in Duchenne muscular dystrophy.
af: Hirst, R, et al.
Udgivet: (2005)

Alternative utrophin mRNAs contribute to phenotypic differences between dystrophin-deficient mice and Duchenne muscular dystrophy
af: Perkins, K, et al.
Udgivet: (2018)

Non-uniform dystrophin re-expression after CRISPR-mediated exon excision in the dystrophin/utrophin double-knockout mouse model of DMD
af: Hanson, B, et al.
Udgivet: (2022)

Utrophin in the therapy of Duchenne Muscular Dystrophy
af: Potter, A, et al.
Udgivet: (2006)

Microarray analysis of mdx mice expressing high levels of utrophin: therapeutic implications for dystrophin deficiency.
af: Baban, D, et al.
Udgivet: (2008)

PMO-based let-7c site blocking oligonucleotide (SBO) mediated utrophin upregulation in mdx mice, a therapeutic approach for Duchenne muscular dystrophy (DMD)
af: Kasturi Sengupta, et al.
Udgivet: (2020-12-01)

The artificial zinc finger coding gene 'Jazz' binds the utrophin promoter and activates transcription.
af: Corbi, N, et al.
Udgivet: (2000)

Non-uniform dystrophin re-expression after CRISPR-mediated exon excision in the dystrophin/utrophin double-knockout mouse model of DMD
af: Britt Hanson, et al.
Udgivet: (2022-12-01)

Prevention of the dystrophic phenotype in dystrophin/utrophin-deficient muscle following adenovirus-mediated transfer of a utrophin minigene.
af: Wakefield, P, et al.
Udgivet: (2000)

A- and B-utrophin have different expression patterns and are differentially up-regulated in mdx muscle.
af: Weir, A, et al.
Udgivet: (2002)

Regulation of utrophin in transgenic mice (multiple letters)
af: Davies, K, et al.
Udgivet: (2005)

Current status of pharmaceutical and genetic therapeutic approaches to treat DMD
af: Pichavant, C, et al.
Udgivet: (2011)

Current status of pharmaceutical and genetic therapeutic approaches to treat DMD.
af: Pichavant, C, et al.
Udgivet: (2011)

Non-toxic ubiquitous overexpression of utrophin in the mdx mouse.
af: Fisher, R, et al.
Udgivet: (2000)

The utrophin and dystrophin genes share similarities in genomic structure.
af: Pearce, M, et al.
Udgivet: (1993)

Utrophin influences mitochondrial pathology and oxidative stress in dystrophic muscle
af: Kennedy, T, et al.
Udgivet: (2017)

Non-toxic ubiquitous over-expression of utrophin in the mdx mouse.
af: Fisher, R, et al.
Udgivet: (2001)

The potential of utrophin and dystrophin combination therapies for Duchenne muscular dystrophy
af: Guiraud, S, et al.
Udgivet: (2019)

Metabolic profiles of dystrophin and utrophin expression in mouse models of Duchenne muscular dystrophy.
af: Griffin, J, et al.
Udgivet: (2002)

A quantitative study of bioenergetics in skeletal muscle lacking utrophin and dystrophin.
af: Cole, M, et al.
Udgivet: (2002)