Novel 5 '-utrophin isoforms exhibit species-specific transcriptional profiles and provide additional candidates for therapeutic up-regulation in DMD

Novel 5 '-utrophin isoforms exhibit species-specific transcriptional profiles and provide additional candidates for therapeutic up-regulation in DMD

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Perkins, K, Proudfoot, N, Davies, K
Μορφή:	Conference item
Έκδοση:	2012

Παρόμοια τεκμήρια

Analysis of the transcriptional control of utrophin promoters as a therapeutic strategy for Duchenne muscular dystrophy (DMD).
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Second-generation compound for the modulation of utrophin in the therapy of DMD
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Identification of serum protein biomarkers for utrophin based DMD therapy.
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Utrophin upregulation in DMD therapy: current status and new tools for the future
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The role of basal and myogenic factors in the transcriptional activation of utrophin promoter A: implications for therapeutic up-regulation in Duchenne muscular dystrophy.
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Embryonic myosin is a regeneration marker to monitor utrophin-based therapies for DMD
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Utrophin up-regulation by an artificial transcription factor in transgenic mice
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New orally available compounds which modulate utrophin expression for the therapy of Duchenne muscular dystrophy (DMD)
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The role of utrophin in the potential therapy of Duchenne muscular dystrophy.
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Utrophin up-regulation by an artificial transcription factor in transgenic mice.
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Expression of different isoforms of utrophin in human muscle; potentials for therapy of Duchenne muscular dystrophy
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Future clinical and biomarker development for SMTC1100, the first utrophin modulator to enter clinical trials for Duchenne Muscular Dystrophy (DMD)
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A and B utrophin in human muscle and sarcolemmal A-utrophin associated with tumours.
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Regulation of utrophin in transgenic mice.
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A-utrophin up-regulation in mdx skeletal muscle is independent of regeneration.
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Sertoli Cells Improve Myogenic Differentiation, Reduce Fibrogenic Markers, and Induce Utrophin Expression in Human DMD Myoblasts
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Up-regulation of utrophin alleviates the dystrophic phenotype in the mdx mouse heart
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Understanding the endothelial function of utrophin.
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Ets, Ap-1 and GATA factor families regulate the utrophin B promoter: potential regulatory mechanisms for endothelial-specific expression.
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Utrophin luciferase knock-in mouse model for in vivo assessment of drug efficacy in preclinical trials for utrophin upregulation
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Utrophin upregulation in Duchenne muscular dystrophy.
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Alternative utrophin mRNAs contribute to phenotypic differences between dystrophin-deficient mice and Duchenne muscular dystrophy
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Non-uniform dystrophin re-expression after CRISPR-mediated exon excision in the dystrophin/utrophin double-knockout mouse model of DMD
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Utrophin in the therapy of Duchenne Muscular Dystrophy
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Microarray analysis of mdx mice expressing high levels of utrophin: therapeutic implications for dystrophin deficiency.
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PMO-based let-7c site blocking oligonucleotide (SBO) mediated utrophin upregulation in mdx mice, a therapeutic approach for Duchenne muscular dystrophy (DMD)
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The artificial zinc finger coding gene 'Jazz' binds the utrophin promoter and activates transcription.
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Non-uniform dystrophin re-expression after CRISPR-mediated exon excision in the dystrophin/utrophin double-knockout mouse model of DMD
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A- and B-utrophin have different expression patterns and are differentially up-regulated in mdx muscle.
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Regulation of utrophin in transgenic mice (multiple letters)
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Current status of pharmaceutical and genetic therapeutic approaches to treat DMD
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Current status of pharmaceutical and genetic therapeutic approaches to treat DMD.
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Non-toxic ubiquitous overexpression of utrophin in the mdx mouse.
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The utrophin and dystrophin genes share similarities in genomic structure.
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Utrophin influences mitochondrial pathology and oxidative stress in dystrophic muscle
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Non-toxic ubiquitous over-expression of utrophin in the mdx mouse.
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A quantitative study of bioenergetics in skeletal muscle lacking utrophin and dystrophin.
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