Probabilistic patient monitoring using extreme value theory: A multivariate, multimodal methodology for detecting patient deterioration

Conventional patient monitoring is performed by generating alarms when vital signs exceed pie-determined thresholds, but the false-alarm rate of such monitors in hospitals is so high that alarms are typically ignored. We propose a principled, probabilistic method for combining vital signs into a mul...

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Main Authors: Hugueny, S, Clifton, D, Tarassenko, L
Format: Journal article
Language:English
Published: 2010
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author Hugueny, S
Clifton, D
Tarassenko, L
author_facet Hugueny, S
Clifton, D
Tarassenko, L
author_sort Hugueny, S
collection OXFORD
description Conventional patient monitoring is performed by generating alarms when vital signs exceed pie-determined thresholds, but the false-alarm rate of such monitors in hospitals is so high that alarms are typically ignored. We propose a principled, probabilistic method for combining vital signs into a multivariate model of patient state, using extreme value theory (EVT) to generate robust alarms if a patient's vital signs are deemed to have become sufficiently "extreme". Our proposed formulation operates many orders of magnitude faster than existing methods, allowing on-line learning of models, leading ultimately to patient-specific monitoring.
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spelling oxford-uuid:11e240fc-e62a-4a5e-b795-9be2fa8443f42022-03-26T10:04:42ZProbabilistic patient monitoring using extreme value theory: A multivariate, multimodal methodology for detecting patient deteriorationJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:11e240fc-e62a-4a5e-b795-9be2fa8443f4EnglishSymplectic Elements at Oxford2010Hugueny, SClifton, DTarassenko, LConventional patient monitoring is performed by generating alarms when vital signs exceed pie-determined thresholds, but the false-alarm rate of such monitors in hospitals is so high that alarms are typically ignored. We propose a principled, probabilistic method for combining vital signs into a multivariate model of patient state, using extreme value theory (EVT) to generate robust alarms if a patient's vital signs are deemed to have become sufficiently "extreme". Our proposed formulation operates many orders of magnitude faster than existing methods, allowing on-line learning of models, leading ultimately to patient-specific monitoring.
spellingShingle Hugueny, S
Clifton, D
Tarassenko, L
Probabilistic patient monitoring using extreme value theory: A multivariate, multimodal methodology for detecting patient deterioration
title Probabilistic patient monitoring using extreme value theory: A multivariate, multimodal methodology for detecting patient deterioration
title_full Probabilistic patient monitoring using extreme value theory: A multivariate, multimodal methodology for detecting patient deterioration
title_fullStr Probabilistic patient monitoring using extreme value theory: A multivariate, multimodal methodology for detecting patient deterioration
title_full_unstemmed Probabilistic patient monitoring using extreme value theory: A multivariate, multimodal methodology for detecting patient deterioration
title_short Probabilistic patient monitoring using extreme value theory: A multivariate, multimodal methodology for detecting patient deterioration
title_sort probabilistic patient monitoring using extreme value theory a multivariate multimodal methodology for detecting patient deterioration
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AT cliftond probabilisticpatientmonitoringusingextremevaluetheoryamultivariatemultimodalmethodologyfordetectingpatientdeterioration
AT tarassenkol probabilisticpatientmonitoringusingextremevaluetheoryamultivariatemultimodalmethodologyfordetectingpatientdeterioration