A global optimisation method for robust affine registration of brain images.

Registration is an important component of medical image analysis and for analysing large amounts of data it is desirable to have fully automatic registration methods. Many different automatic registration methods have been proposed to date, and almost all share a common mathematical framework - one...

Full description

Bibliographic Details
Main Authors: Jenkinson, M, Smith, S
Format: Journal article
Language:English
Published: 2001
_version_ 1826259837593321472
author Jenkinson, M
Smith, S
author_facet Jenkinson, M
Smith, S
author_sort Jenkinson, M
collection OXFORD
description Registration is an important component of medical image analysis and for analysing large amounts of data it is desirable to have fully automatic registration methods. Many different automatic registration methods have been proposed to date, and almost all share a common mathematical framework - one of optimising a cost function. To date little attention has been focused on the optimisation method itself, even though the success of most registration methods hinges on the quality of this optimisation. This paper examines the assumptions underlying the problem of registration for brain images using inter-modal voxel similarity measures. It is demonstrated that the use of local optimisation methods together with the standard multi-resolution approach is not sufficient to reliably find the global minimum. To address this problem, a global optimisation method is proposed that is specifically tailored to this form of registration. A full discussion of all the necessary implementation details is included as this is an important part of any practical method. Furthermore, results are presented for inter-modal, inter-subject registration experiments that show that the proposed method is more reliable at finding the global minimum than several of the currently available registration packages in common usage.
first_indexed 2024-03-06T18:56:06Z
format Journal article
id oxford-uuid:11e4da81-0ddf-4219-9a14-85451fdfc906
institution University of Oxford
language English
last_indexed 2024-03-06T18:56:06Z
publishDate 2001
record_format dspace
spelling oxford-uuid:11e4da81-0ddf-4219-9a14-85451fdfc9062022-03-26T10:04:45ZA global optimisation method for robust affine registration of brain images.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:11e4da81-0ddf-4219-9a14-85451fdfc906EnglishSymplectic Elements at Oxford2001Jenkinson, MSmith, SRegistration is an important component of medical image analysis and for analysing large amounts of data it is desirable to have fully automatic registration methods. Many different automatic registration methods have been proposed to date, and almost all share a common mathematical framework - one of optimising a cost function. To date little attention has been focused on the optimisation method itself, even though the success of most registration methods hinges on the quality of this optimisation. This paper examines the assumptions underlying the problem of registration for brain images using inter-modal voxel similarity measures. It is demonstrated that the use of local optimisation methods together with the standard multi-resolution approach is not sufficient to reliably find the global minimum. To address this problem, a global optimisation method is proposed that is specifically tailored to this form of registration. A full discussion of all the necessary implementation details is included as this is an important part of any practical method. Furthermore, results are presented for inter-modal, inter-subject registration experiments that show that the proposed method is more reliable at finding the global minimum than several of the currently available registration packages in common usage.
spellingShingle Jenkinson, M
Smith, S
A global optimisation method for robust affine registration of brain images.
title A global optimisation method for robust affine registration of brain images.
title_full A global optimisation method for robust affine registration of brain images.
title_fullStr A global optimisation method for robust affine registration of brain images.
title_full_unstemmed A global optimisation method for robust affine registration of brain images.
title_short A global optimisation method for robust affine registration of brain images.
title_sort global optimisation method for robust affine registration of brain images
work_keys_str_mv AT jenkinsonm aglobaloptimisationmethodforrobustaffineregistrationofbrainimages
AT smiths aglobaloptimisationmethodforrobustaffineregistrationofbrainimages
AT jenkinsonm globaloptimisationmethodforrobustaffineregistrationofbrainimages
AT smiths globaloptimisationmethodforrobustaffineregistrationofbrainimages