Reproducible and scalable purification of extracellular vesicles using combined bind-elute and size exclusion chromatography

Extracellular vesicles (EVs) play a pivotal role in cell-to-cell communication and have been shown to take part in several physiological and pathological processes. EVs have traditionally been purified by ultracentrifugation (UC), however UC has limitations, including resulting in, operator-dependan...

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Main Authors: Corso, G, Mäger, I, Lee, Y, Görgens, A, Bultema, J, Giebel, B, Wood, M, Nordin, J, Andaloussi, S
格式: Journal article
语言:English
出版: Springer Nature 2017