Development of a non-human primate BCG infection model for the evaluation of candidate tuberculosis vaccines

The lack of validated immunological correlates of protection makes tuberculosis vaccine development difficult and expensive. Using intradermal bacille Calmette-Guréin (BCG) as a surrogate for aerosol Mycobacterium tuberculosis (M.tb) in a controlled human infection model could facilitate vaccine dev...

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Hlavní autoři: Harris, S, White, A, Stockdale, L, Tanner, R, Sibley, L, Sarfas, C, Meyer, J, Peter, J, O'Shea, M, Manjaly Thomas, Z, Hamidi, A, Satti, I, Dennis, M, McShane, H, Sharpe, S
Médium: Journal article
Vydáno: Elsevier 2017

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