Development of a non-human primate BCG infection model for the evaluation of candidate tuberculosis vaccines

Development of a non-human primate BCG infection model for the evaluation of candidate tuberculosis vaccines

The lack of validated immunological correlates of protection makes tuberculosis vaccine development difficult and expensive. Using intradermal bacille Calmette-Guréin (BCG) as a surrogate for aerosol Mycobacterium tuberculosis (M.tb) in a controlled human infection model could facilitate vaccine dev...

Повний опис

Бібліографічні деталі
Автори:	Harris, S, White, A, Stockdale, L, Tanner, R, Sibley, L, Sarfas, C, Meyer, J, Peter, J, O'Shea, M, Manjaly Thomas, Z, Hamidi, A, Satti, I, Dennis, M, McShane, H, Sharpe, S
Формат:	Journal article
Опубліковано:	Elsevier 2017

Схожі ресурси

A non-human primate in vitro functional assay for the early evaluation of TB vaccine candidates
за авторством: Tanner, R, та інші
Опубліковано: (2021)

Optimisation of a human BCG challenge model
за авторством: Wilkie, M, та інші
Опубліковано: (2015)

MTBVAC induces superior antibody titers and IgG avidity compared to BCG vaccination in non-human primates
за авторством: Peralta-Álvarez, MP, та інші
Опубліковано: (2024)

Evaluation of a human BCG challenge model to assess antimycobacterial immunity induced by BCG and a candidate TB vaccine, MVA85A, alone and in combination
за авторством: Harris, S, та інші
Опубліковано: (2013)

Evaluation of a human BCG challenge model to assess antimycobacterial immunity induced by BCG and a candidate tuberculosis vaccine, MVA85A, alone and in combination.
за авторством: Harris, SA, та інші
Опубліковано: (2014)

MTBVAC induces superior antibody titers and IgG avidity compared to BCG vaccination in non-human primates
за авторством: Marco Polo Peralta-Álvarez, та інші
Опубліковано: (2024-11-01)

The in vitro direct mycobacterial growth inhibition assay (MGIA) for the early evaluation of TB vaccine candidates and assessment of protective immunity: a protocol for non-human primate cells
за авторством: Tanner, R, та інші
Опубліковано: (2021)

A non-human primate in vitro functional assay for the early evaluation of TB vaccine candidates
за авторством: Rachel Tanner, та інші
Опубліковано: (2021-01-01)

Low-dose M.tb infection but not BCG or MTBVAC vaccination enhances heterologous antibody titres in non-human primates
за авторством: Alvarez, MPP, та інші
Опубліковано: (2024)

A first-in-human phase 1 trial to evaluate the safety and immunogenicity of the candidate tuberculosis vaccine MVA85A-IMX313, administered to BCG-vaccinated adults.
за авторством: Minhinnick, A, та інші
Опубліковано: (2016)

Low-dose M.tb infection but not BCG or MTBVAC vaccination enhances heterologous antibody titres in non-human primates
за авторством: Marco Polo Peralta Alvarez, та інші
Опубліковано: (2024-05-01)

The in vitro direct mycobacterial growth inhibition assay (MGIA) for the early evaluation of TB vaccine candidates and assessment of protective immunity: a protocol for non-human primate cells [version 1; peer review: 2 approved]
за авторством: Rachel Tanner, та інші
Опубліковано: (2021-03-01)

The in vitro direct mycobacterial growth inhibition assay (MGIA) for the early evaluation of TB vaccine candidates and assessment of protective immunity: a protocol for non-human primate cells [version 2; peer review: 2 approved]
за авторством: Rachel Tanner, та інші
Опубліковано: (2021-09-01)

Gene expression and cytokine profile correlate with mycobacterial growth in a human BCG challenge model
за авторством: Matsumiya, M, та інші
Опубліковано: (2014)

Immune cell population dynamics following neonatal BCG vaccination and aerosol BCG revaccination in rhesus macaques
за авторством: Laura Sibley, та інші
Опубліковано: (2024-07-01)

A Phase I, Open-Label Trial, Evaluating the Safety and Immunogenicity of Candidate Tuberculosis Vaccines AERAS-402 and MVA85A, Administered by Prime-Boost Regime in BCG-Vaccinated Healthy Adults
за авторством: Sheehan, S, та інші
Опубліковано: (2015)

Safety and immunogenicity of a candidate tuberculosis vaccine MVA85A delivered by aerosol in BCG-vaccinated healthy adults: a phase 1, double-blind, randomised controlled trial.
за авторством: Satti, I, та інші
Опубліковано: (2014)

Spore-FP1 tuberculosis mucosal vaccine candidate is highly protective in guinea pigs but fails to improve on BCG-conferred protection in non-human primates
за авторством: Andrew D. White, та інші
Опубліковано: (2023-10-01)

Development of a primate model for tuberculosis vaccine research: IFN-gamma responses induced by BCG vaccination and M-tuberculosis infection in macaques
за авторством: Dowall, S, та інші
Опубліковано: (2007)

Induction of functional specific antibodies, IgG-secreting plasmablasts and memory B cells following BCG vaccination
за авторством: Bitencourt, J, та інші
Опубліковано: (2021)

IV BCG Vaccination and Aerosol BCG Revaccination Induce Mycobacteria-Responsive γδ T Cells Associated with Protective Efficacy against <i>M. tb</i> Challenge
за авторством: Alexandra L. Morrison, та інші
Опубліковано: (2023-10-01)

T-cell activation is an immune correlate of risk in BCG vaccinated infants
за авторством: Fletcher, H, та інші
Опубліковано: (2016)

Predicting IFN-γ responses after BCG vaccination in humans from macaques: A proof-of-concept study of Immunostimulation/Immunodynamic modelling methods
за авторством: Rhodes, S, та інші
Опубліковано: (2017)

Comparison of the safety and immunogenicity of a candidate TB vaccine, MVA85A, given by the intramuscular or intradermal route in BCG-vaccinated adults
за авторством: Harris, S, та інші
Опубліковано: (2011)

Corrigendum: T-cell activation is an immune correlate of risk in BCG vaccinated infants.
за авторством: Fletcher, H, та інші
Опубліковано: (2016)

Inhibition of mycobacterial growth in vitro following primary but not secondary vaccination with Mycobacterium bovis BCG.
за авторством: Fletcher, H, та інші
Опубліковано: (2013)

Development of a BCG challenge model for the testing of vaccine candidates against tuberculosis in cattle
за авторством: Villarreal-Ramos, B, та інші
Опубліковано: (2017)

Process of Assay Selection and Optimization for the Study of Case and Control Samples from a Phase IIb Efficacy Trial of a Candidate Tuberculosis Vaccine, MVA85A
за авторством: Harris, SA, та інші
Опубліковано: (2014)

Safety and immunogenicity of a candidate tuberculosis vaccine MVA85A delivered by aerosol in BCG-vaccinated healthy adults: A phase 1, double-blind, randomised controlled trial
за авторством: Satti, I, та інші
Опубліковано: (2014)

Characterization of the Infant Immune System and the Influence and Immunogenicity of BCG Vaccination in Infant and Adult Rhesus Macaques
за авторством: Charlotte Sarfas, та інші
Опубліковано: (2021-10-01)

The humoral immune response to BCG vaccination
за авторством: Tanner, R, та інші
Опубліковано: (2019)

Immunological correlates of mycobacterial growth inhibition describe a spectrum of tuberculosis infection
за авторством: O'Shea, M, та інші
Опубліковано: (2018)

Revaccination with BCG: does it work?
за авторством: McShane, H
Опубліковано: (2024)

Understanding BCG is the key to improving it.
за авторством: McShane, H
Опубліковано: (2013)

Induction of Functional Specific Antibodies, IgG-Secreting Plasmablasts and Memory B Cells Following BCG Vaccination
за авторством: Julia Bitencourt, та інші
Опубліковано: (2022-01-01)

T-cell activation is an immune correlate of risk in BCG vaccinated infants
за авторством: Helen A. Fletcher, та інші
Опубліковано: (2016-04-01)

Inflammation and immune activation are associated with risk of Mycobacterium tuberculosis infection in BCG-vaccinated infants
за авторством: Satti, I, та інші
Опубліковано: (2022)

Optimization of a human bacille Calmette-Guerin challenge model: a tool to evaluate antimycobacterial immunity
за авторством: Minhinnick, A, та інші
Опубліковано: (2015)

Preclinical development of an in vivo BCG challenge model for testing candidate TB vaccine efficacy.
за авторством: Minassian, A, та інші
Опубліковано: (2011)

TB and SIV Coinfection; a Model for Evaluating Vaccine Strategies against TB Reactivation in Asian Origin Cynomolgus Macaques: A Pilot Study Using BCG Vaccination
за авторством: Andrew D. White, та інші
Опубліковано: (2021-08-01)