Severe but reversible neuropathy and encephalopathy due to vitamin E deficiency
Vitamin E deficiency is known to result mainly in a spinocerebellar syndrome and involvement of the peripheral nervous system occurs less commonly. Most cases of vitamin E-deficient ataxic neuropathy reported relate to a genetically-mediated cause through mutation of the alpha-tocopherol transfer pr...
| প্রধান লেখক: | , , , , |
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| বিন্যাস: | Journal article |
| ভাষা: | English |
| প্রকাশিত: |
Elsevier
2017
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| সংক্ষিপ্ত: | Vitamin E deficiency is known to result mainly in a spinocerebellar syndrome and involvement of the peripheral nervous system occurs less commonly. Most cases of vitamin E-deficient ataxic neuropathy reported relate to a genetically-mediated cause through mutation of the alpha-tocopherol transfer protein (TTPA) gene on chromosome 8q13 [1]. Severe subacute adult-onset rapidly disabling neuropathy due to vitamin E deficiency is not to our knowledge reported. Cognitive dysfunction is uncommon in this setting. Occurrence of isolated ymptomatic vitamin E deficiency due to pancreatic exocrine insufficiency (PEI) appears exceptional. |
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