Severe but reversible neuropathy and encephalopathy due to vitamin E deficiency
Vitamin E deficiency is known to result mainly in a spinocerebellar syndrome and involvement of the peripheral nervous system occurs less commonly. Most cases of vitamin E-deficient ataxic neuropathy reported relate to a genetically-mediated cause through mutation of the alpha-tocopherol transfer pr...
| Main Authors: | , , , , |
|---|---|
| Format: | Journal article |
| Sprog: | English |
| Udgivet: |
Elsevier
2017
|
| _version_ | 1826259873558429696 |
|---|---|
| author | Wysota, B Michael, S Hiew, FL Dawson, C Rajabally, YA |
| author_facet | Wysota, B Michael, S Hiew, FL Dawson, C Rajabally, YA |
| author_sort | Wysota, B |
| collection | OXFORD |
| description | Vitamin E deficiency is known to result mainly in a spinocerebellar syndrome and involvement of the peripheral nervous system occurs less commonly. Most cases of vitamin E-deficient ataxic neuropathy reported relate to a genetically-mediated cause through mutation of the alpha-tocopherol transfer protein (TTPA) gene on chromosome 8q13 [1]. Severe subacute adult-onset rapidly disabling neuropathy due to vitamin E deficiency is not to our knowledge reported. Cognitive dysfunction is uncommon in this setting. Occurrence of isolated ymptomatic vitamin E deficiency due to pancreatic exocrine insufficiency (PEI) appears exceptional. |
| first_indexed | 2024-03-06T18:56:41Z |
| format | Journal article |
| id | oxford-uuid:1213eb7e-65cb-428c-82f9-a8df5603550e |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T18:56:41Z |
| publishDate | 2017 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | oxford-uuid:1213eb7e-65cb-428c-82f9-a8df5603550e2022-03-26T10:05:49ZSevere but reversible neuropathy and encephalopathy due to vitamin E deficiencyJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:1213eb7e-65cb-428c-82f9-a8df5603550eEnglishSymplectic ElementsElsevier2017Wysota, BMichael, SHiew, FLDawson, CRajabally, YAVitamin E deficiency is known to result mainly in a spinocerebellar syndrome and involvement of the peripheral nervous system occurs less commonly. Most cases of vitamin E-deficient ataxic neuropathy reported relate to a genetically-mediated cause through mutation of the alpha-tocopherol transfer protein (TTPA) gene on chromosome 8q13 [1]. Severe subacute adult-onset rapidly disabling neuropathy due to vitamin E deficiency is not to our knowledge reported. Cognitive dysfunction is uncommon in this setting. Occurrence of isolated ymptomatic vitamin E deficiency due to pancreatic exocrine insufficiency (PEI) appears exceptional. |
| spellingShingle | Wysota, B Michael, S Hiew, FL Dawson, C Rajabally, YA Severe but reversible neuropathy and encephalopathy due to vitamin E deficiency |
| title | Severe but reversible neuropathy and encephalopathy due to vitamin E deficiency |
| title_full | Severe but reversible neuropathy and encephalopathy due to vitamin E deficiency |
| title_fullStr | Severe but reversible neuropathy and encephalopathy due to vitamin E deficiency |
| title_full_unstemmed | Severe but reversible neuropathy and encephalopathy due to vitamin E deficiency |
| title_short | Severe but reversible neuropathy and encephalopathy due to vitamin E deficiency |
| title_sort | severe but reversible neuropathy and encephalopathy due to vitamin e deficiency |
| work_keys_str_mv | AT wysotab severebutreversibleneuropathyandencephalopathyduetovitaminedeficiency AT michaels severebutreversibleneuropathyandencephalopathyduetovitaminedeficiency AT hiewfl severebutreversibleneuropathyandencephalopathyduetovitaminedeficiency AT dawsonc severebutreversibleneuropathyandencephalopathyduetovitaminedeficiency AT rajaballyya severebutreversibleneuropathyandencephalopathyduetovitaminedeficiency |