Interactions among HIV gp120, CD4, and CXCR4: dependence on CD4 expression level, gp120 viral origin, conservation of the gp120 COOH- and NH2-termini and V1/V2 and V3 loops, and sensitivity to neutralizing antibodies.

Interactions among HIV gp120, CD4, and CXCR4: dependence on CD4 expression level, gp120 viral origin, conservation of the gp120 COOH- and NH2-termini and V1/V2 and V3 loops, and sensitivity to neutralizing antibodies.

The binding of HIV-derived recombinant soluble (s)gp120 to the CD4(+)/CXCR4(+) A3.01 T cell line inhibits the binding of the CXCR4-specific monoclonal antibodies 12G5, which interacts with the second extracellular loop, and 6H8, which binds the NH2 terminus. We have used this as an assay to analyse...

Mô tả đầy đủ

Chi tiết về thư mục
Những tác giả chính:	Mondor, I, Moulard, M, Ugolini, S, Klasse, P, Hoxie, J, Amara, A, Delaunay, T, Wyatt, R, Sodroski, J, Sattentau, Q
Định dạng:	Journal article
Ngôn ngữ:	English
Được phát hành:	1998

Những quyển sách tương tự

HIV-1 gp120 induces an association between CD4 and the chemokine receptor CXCR4.
Bằng: Ugolini, S, et al.
Được phát hành: (1997)

Cyanovirin-N binds to gp120 to interfere with CD4-dependent human immunodeficiency virus type 1 virion binding, fusion, and infectivity but does not affect the CD4 binding site on gp120 or soluble CD4-induced conformational changes in gp120.
Bằng: Esser, M, et al.
Được phát hành: (1999)

Conformational transitions in CD4 due to complexation with HIV envelope glycoprotein gp120.
Bằng: Denisova, G, et al.
Được phát hành: (1997)

Characterization of gp120 and Its Single-chain Derivatives, gp120-CD4 and gp120-M9: Implications for Targeting the CD4i Epitope in HIV-1 Vaccine Design
Bằng: Shiver John
Được phát hành: (2005-12-01)

Human immunodeficiency virus type 1 attachment to HeLa CD4 cells is CD4 independent and gp120 dependent and requires cell surface heparans.
Bằng: Mondor, I, et al.
Được phát hành: (1998)

Interactions of HIV gp120 with the CD4 molecule on lymphocytes and in the nervous system.
Bằng: Sattentau, Q
Được phát hành: (1990)

INTERACTIONS OF HIV GP120 WITH THE CD4 MOLECULE ON LYMPHOCYTES AND IN THE NERVOUS-SYSTEM
Bằng: Sattentau, Q
Được phát hành: (1990)

Detecting SIV gp120 and its interaction with soluble CD4 by ELISA.
Bằng: Moore, J, et al.
Được phát hành: (1993)

SOLUBLE CD4 BINDING TO HIV-1 VIRIONS CAUSES GP120 TO DISSOCIATE FROM GP41
Bằng: Moore, J, et al.
Được phát hành: (1991)

STRUCTURAL-ANALYSIS OF THE HIV GP120 BINDING DOMAIN OF THE CD4 RECEPTOR
Bằng: Arthos, J, et al.
Được phát hành: (1990)

Antibodies to the CD4-binding site of HIV-1 gp120 suppress gp120-specific CD4 T cell response while enhancing antibody response
Bằng: Hioe Catarina E, et al.
Được phát hành: (2008-07-01)

Dissociation of gp120 from HIV-1 virions induced by soluble CD4.
Bằng: Moore, J, et al.
Được phát hành: (1990)

Monoclonal antibodies to HIV-1 gp120: a request.
Bằng: Moore, J, et al.
Được phát hành: (1993)

Enhancement of soluble CD4-mediated HIV neutralization and gp 120 binding by CD4 autoantibodies and monoclonal antibodies.
Bằng: Moore, J, et al.
Được phát hành: (1990)

Selective interactions of polyanions with basic surfaces on human immunodeficiency virus type 1 gp120.
Bằng: Moulard, M, et al.
Được phát hành: (2000)

STRUCTURAL-ANALYSIS OF THE HIV-1 ENVELOPE GLYCOPROTEIN GP120
Bằng: Moore, J, et al.
Được phát hành: (1993)

A PREDICTED 3-DIMENSIONAL STRUCTURE OF CD4 AND THE LOCATION OF THE HIV GP120 BINDING REGION
Bằng: Mcgregor, M, et al.
Được phát hành: (1990)

Conformational alterations in the CD4 binding cavity of HIV-1 gp120 influencing gp120-CD4 interactions and fusogenicity of HIV-1 envelopes derived from brain and other tissues
Bằng: Ramsland Paul A, et al.
Được phát hành: (2011-06-01)

The first structure of HIV-1 gp120 with CD4 and CCR5 receptors
Bằng: Yongjun Guan
Được phát hành: (2019-01-01)

Select gp120 V2 domain specific antibodies derived from HIV and SIV infection and vaccination inhibit gp120 binding to α4β7.
Bằng: Sakaorat Lertjuthaporn, et al.
Được phát hành: (2018-08-01)

Allosteric modulation of the HIV-1 gp120-gp41 association site by adjacent gp120 variable region 1 (V1) N-glycans linked to neutralization sensitivity.
Bằng: Heidi E Drummer, et al.
Được phát hành: (2013-01-01)

The recognition of chimeras of rat and human CD4 by HIV-1 gp120 and by monoclonal antibodies.
Bằng: Davis, S, et al.
Được phát hành: (1993)

Fusion Complexes and CD4-independent gp120s for the Induction of HIV-1 Neutralizing Antibodies
Bằng: Lopalco L, et al.
Được phát hành: (2005-12-01)

CD4-Induced conformational changes in the human immunodeficiency virus type 1 gp120 glycoprotein: consequences for virus entry and neutralization.
Bằng: Sullivan, N, et al.
Được phát hành: (1998)

CXCR4 Recognition by L- and D-Peptides Containing the Full-Length V3 Loop of HIV-1 gp120
Bằng: Ruohan Zhu, et al.
Được phát hành: (2023-04-01)

Towards a structure of the HIV-1 envelope glycoprotein gp120: an immunochemical approach.
Bằng: Moore, J, et al.
Được phát hành: (1993)

Oligomeric modeling and electrostatic analysis of the gp120 envelope glycoprotein of human immunodeficiency virus.
Bằng: Kwong, P, et al.
Được phát hành: (2000)

HIV gp120: double lock strategy foils host defences.
Bằng: Sattentau, Q
Được phát hành: (1998)

Role of anti-CD4-binding site antibodies in modulating gp120-specific CD4 T cell and antibody responses
Bằng: Gorny MK, et al.
Được phát hành: (2006-12-01)

Stronger binding affinities of gp120/CD4 in Catarrhini provide insights into HIV/host interactions
Bằng: Vladimir Li, et al.
Được phát hành: (2025-03-01)

Effect of site-specific de-glycosylation on HIV gp120-specific CD4 T cell responses
Bằng: Visciano Maria, et al.
Được phát hành: (2006-12-01)

Probing the structure of the human immunodeficiency virus surface glycoprotein gp120 with a panel of monoclonal antibodies.
Bằng: Moore, J, et al.
Được phát hành: (1994)

Primary isolates of human immunodeficiency virus type 1 are relatively resistant to neutralization by monoclonal antibodies to gp120, and their neutralization is not predicted by studies with monomeric gp120.
Bằng: Moore, J, et al.
Được phát hành: (1995)

Role of CD4 epitopes outside the gp120-binding site during entry of human immunodeficiency virus type 1.
Bằng: Simon, J, et al.
Được phát hành: (1997)

Conservation of HIV-1 gp120 neutralizing epitopes after formalin inactivation.
Bằng: Sattentau, Q
Được phát hành: (1995)

The HIV-1 Env gp120 Inner Domain Shapes the Phe43 Cavity and the CD4 Binding Site
Bằng: Jérémie Prévost, et al.
Được phát hành: (2020-06-01)

Physiological Corticosterone Attenuates gp120-Mediated Microglial Activation and Is Associated with Reduced Anxiety-Like Behavior in gp120-Expressing Mice
Bằng: Emaya M. Moss, et al.
Được phát hành: (2023-02-01)

Cryptic determinant of α4β7 binding in the V2 loop of HIV-1 gp120.
Bằng: Boonrat Tassaneetrithep, et al.
Được phát hành: (2014-01-01)

Construction of a binding site for human immunodeficiency virus type 1 gp120 in rat CD4.
Bằng: Schockmel, G, et al.
Được phát hành: (1992)

Antibody and HIV-1 gp120 recognition of CD4 undermines the concept of mimicry between antibodies and receptors.
Bằng: Davis, S, et al.
Được phát hành: (1992)