Truncated CPSF6 forms higher order complexes that bind and disrupt HIV-1 capsid

Cleavage and polyadenylation specificity factor 6 (CPSF6) is a human protein that binds HIV-1 capsid and mediates nuclear transport and integration targeting of HIV-1 pre-integration complexes. Truncation of the protein at its C-terminal nuclear-targeting arginine/serine-rich (RS-) domain produces a...

সম্পূর্ণ বিবরণ

গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Ning, J, Zhong, Z, Fischer, D, Harris, G, Watkins, S, Ambrose, Z, Zhang, P
বিন্যাস: Journal article
ভাষা:English
প্রকাশিত: American Society for Microbiology 2018