Truncated CPSF6 forms higher order complexes that bind and disrupt HIV-1 capsid

Truncated CPSF6 forms higher order complexes that bind and disrupt HIV-1 capsid

Cleavage and polyadenylation specificity factor 6 (CPSF6) is a human protein that binds HIV-1 capsid and mediates nuclear transport and integration targeting of HIV-1 pre-integration complexes. Truncation of the protein at its C-terminal nuclear-targeting arginine/serine-rich (RS-) domain produces a...

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Bibliographic Details
Main Authors:	Ning, J, Zhong, Z, Fischer, D, Harris, G, Watkins, S, Ambrose, Z, Zhang, P
Format:	Journal article
Language:	English
Published:	American Society for Microbiology 2018

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