Truncated CPSF6 forms higher order complexes that bind and disrupt HIV-1 capsid
Cleavage and polyadenylation specificity factor 6 (CPSF6) is a human protein that binds HIV-1 capsid and mediates nuclear transport and integration targeting of HIV-1 pre-integration complexes. Truncation of the protein at its C-terminal nuclear-targeting arginine/serine-rich (RS-) domain produces a...
Päätekijät: | Ning, J, Zhong, Z, Fischer, D, Harris, G, Watkins, S, Ambrose, Z, Zhang, P |
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Aineistotyyppi: | Journal article |
Kieli: | English |
Julkaistu: |
American Society for Microbiology
2018
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