Quantitative rate measurement of the hydroxide driven dissolution of an enteric drug coating using atomic force microscopy

Quantitative rate measurement of the hydroxide driven dissolution of an enteric drug coating using atomic force microscopy

The hydroxide-driven dissolution of the polymer hydroxypropyl methylcellulose phthalate (HPMCP) in aqueous solution is studied using atomic force microscopy. The novel technique of employing the surface-averaged z-piezo voltage as a direct measure of the mean absolute surface height is described, so...

Полное описание

Библиографические подробности
Главные авторы:	Sanders, G, Booth, J, Compton, R
Формат:	Journal article
Язык:	English
Опубликовано:	1997

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