Quantitative rate measurement of the hydroxide driven dissolution of an enteric drug coating using atomic force microscopy

The hydroxide-driven dissolution of the polymer hydroxypropyl methylcellulose phthalate (HPMCP) in aqueous solution is studied using atomic force microscopy. The novel technique of employing the surface-averaged z-piezo voltage as a direct measure of the mean absolute surface height is described, so...

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Những tác giả chính: Sanders, G, Booth, J, Compton, R
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 1997