Long-term follow-up of the original interferon-beta1b trial in multiple sclerosis: design and lessons from a 16-year observational study.

Long-term follow-up of the original interferon-beta1b trial in multiple sclerosis: design and lessons from a 16-year observational study.

OBJECTIVE: This article describes the design of and difficulties inherent in the execution of a long-term, observational trial that sought to assess the validity of short-term measures of multiple sclerosis (MS) (eg, relapse rate, inflammatory lesions) for long-term disease outcomes. METHODS: In th...

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Detalles Bibliográficos
Autores principales: Ebers, G, Reder, A, Traboulsee, A, Li, D, Langdon, D, Goodin, D, Wolf, C, Beckmann, K, Konieczny, A
Formato: Journal article
Lenguaje:English
Publicado: 2009

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