The neuropathic potential of anti-GM1 autoantibodies is regulated by the local glycolipid environment in mice.
Anti-GM1 ganglioside autoantibodies are used as diagnostic markers for motor axonal peripheral neuropathies and are believed to be the primary mediators of such diseases. However, their ability to bind and exert pathogenic effects at neuronal membranes is highly inconsistent. Using human and mouse m...
Main Authors: | Greenshields, K, Halstead, S, Zitman, F, Rinaldi, S, Brennan, K, O'Leary, C, Chamberlain, L, Easton, A, Roxburgh, J, Pediani, J, Furukawa, K, Goodyear, C, Plomp, J, Willison, H |
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Format: | Journal article |
Language: | English |
Published: |
2009
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