Estimating the number of coding mutations in genotypic- and phenotypic-driven N-ethyl-N-nitrosourea (ENU) screens.

Estimating the number of coding mutations in genotypic- and phenotypic-driven N-ethyl-N-nitrosourea (ENU) screens.

N-ethyl-N-nitrosourea (ENU) is a widely used mutagen in genotypic and phenotypic screens aimed at elucidating gene function. The high rate at which ENU induces point mutations raises the possibility that an observed phenotype may be to the result of another unidentified linked mutation. This article...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Keays, D, Clark, T, Flint, J
Μορφή:	Journal article
Γλώσσα:	English
Έκδοση:	2006

Παρόμοια τεκμήρια

Mutational Analysis of N-Ethyl-N-Nitrosourea (ENU) in the Fission Yeast Schizosaccharomyces pombe
ανά: Rafael Hoyos-Manchado, κ.ά.
Έκδοση: (2020-03-01)

Chromoanasynthetic Genomic Rearrangement Identified in a N-Ethyl-N-Nitrosourea (ENU) Mutagenesis Screen in Caenorhabditis elegans
ανά: Omar A. Itani, κ.ά.
Έκδοση: (2016-02-01)

An N-ethyl-N-nitrosourea (ENU)-induced dominant negative mutation in the JAK3 kinase protects against cerebral malaria.
ανά: Silayuv E Bongfen, κ.ά.
Έκδοση: (2012-01-01)

N-ethyl-N-Nitrosourea (ENU) induced mutations within the klotho gene lead to ectopic calcification and reduced lifespan in mouse models
ανά: Esapa, C, κ.ά.
Έκδοση: (2015)

N-ethyl-N-Nitrosourea (ENU) induced mutations within the klotho gene lead to ectopic calcification and reduced lifespan in mouse models.
ανά: Christopher T Esapa, κ.ά.
Έκδοση: (2015-01-01)

An N-ethyl-N-nitrosourea (ENU) mutagenized mouse model for autosomal dominant non-syndromic kyphoscoliosis due to vertebral fusion
ανά: Esapa, C, κ.ά.
Έκδοση: (2018)

N-Ethyl-N-Nitrosourea (ENU) Mutagenesis Reveals an Intronic Residue Critical for Caenorhabditis elegans 3′ Splice Site Function in Vivo
ανά: Omar A. Itani, κ.ά.
Έκδοση: (2016-06-01)

A mouse with an N-Ethyl-N-nitrosourea (ENU) Induced Trp589Arg Galnt3 mutation represents a model for hyperphosphataemic familial tumoural calcinosis
ανά: Esapa, C, κ.ά.
Έκδοση: (2012)

A mouse with an N-Ethyl-N-nitrosourea (ENU) Induced Trp589Arg Galnt3 mutation represents a model for hyperphosphataemic familial tumoural calcinosis.
ανά: Christopher T Esapa, κ.ά.
Έκδοση: (2012-01-01)

Mice with an N-ethyl-N-nitrosourea (ENU) induced Tyr209Asn mutation in natriuretic peptide receptor 3 (NPR3) provide a model for kyphosis associated with activation of the MAPK signaling pathway
ανά: Esapa, C, κ.ά.
Έκδοση: (2016)

Modulation of autoimmune diabetes by N-ethyl-N-nitrosourea- induced mutations in non-obese diabetic mice
ανά: Lucienne Chatenoud, κ.ά.
Έκδοση: (2022-06-01)

N-ethyl-N-nitrosourea mutagenesis produced a small number of mice with altered plasma electrolyte levels
ανά: Hrabé de Angelis Martin, κ.ά.
Έκδοση: (2009-06-01)

EFFECT OF ETHYL METHANESULFONATE (EMS) AND N-NITROSE-N´-ETHYL UREA (ENU) ON CALLUS GROWTH OF COMMON BEAN
ανά: Diana Lilova SVETLEVA, κ.ά.
Έκδοση: (2005-07-01)

An N-ethyl-N-nitrosourea induced corticotropin-releasing hormone promoter mutation provides a mouse model for endogenous glucocorticoid excess.
ανά: Bentley, L, κ.ά.
Έκδοση: (2014)

An N-ethyl-n-nitrosourea induced corticotropin-releasing hormone promoter mutation provides a mouse model for endogenous glucocorticoid excess
ανά: Bentley, L, κ.ά.
Έκδοση: (2014)

Exposure to N-ethyl-N-nitrosourea in adult mice alters structural and functional integrity of neurogenic sites.
ανά: Vivian Capilla-Gonzalez, κ.ά.
Έκδοση: (2012-01-01)

Spontaneous inflammatory pain model from a mouse line with <it>N</it>-ethyl-<it>N</it>-nitrosourea mutagenesis
ανά: Chen Tsung-Chieh, κ.ά.
Έκδοση: (2012-05-01)

Vanillic acid protects mortality and toxicity induced by N-ethyl-N-nitrosourea in mice; in vivo model of chronic lymphocytic leukemia
ανά: Ahmad Salimi, κ.ά.
Έκδοση: (2024-06-01)

Genomic analysis of microRNA time-course expression in liver of mice treated with genotoxic carcinogen <it>N</it>-ethyl-<it>N</it>-nitrosourea
ανά: Guo Lei, κ.ά.
Έκδοση: (2010-10-01)

N-ethyl-n-nitrosourea induced leukaemia in a mouse model through upregulation of vascular endothelial growth factor and evading apoptosis
ανά: Abdullahi, Aliyu, κ.ά.
Έκδοση: (2020)

N-ethyl-N-nitrosourea-induced adaptor protein 2 sigma subunit 1 ( Ap2s1 ) mutations establish Ap2s1 loss-of-function mice
ανά: Gorvin, C, κ.ά.
Έκδοση: (2017)

Effects of N-methyl-N-nitrosourea on seed germination of Stevia rebaudiana
ανά: Ahmad, Lyena Watty Zuraine, κ.ά.
Έκδοση: (2019)

An N-ethyl-N-Nitrosourea Mutagenesis Screen in Mice Reveals a Mutation in <i>Nuclear Respiratory Factor 1</i> (<i>Nrf1)</i> Altering the DNA Methylation State and Correct Embryonic Development
ανά: Maria Alba Sorolla, κ.ά.
Έκδοση: (2021-07-01)

Probability of phenotypically detectable protein damage by ENU-induced mutations in the Mutagenetix database
ανά: Tao Wang, κ.ά.
Έκδοση: (2018-01-01)

Antimutagenic components in Spatholobus suberectus Dunn against N-methyl-N-nitrosourea
ανά: Keiko Inami, κ.ά.
Έκδοση: (2019-12-01)

Selection of functional EPHB2 genotypes from ENU mutated grass carp treated with GCRV
ανά: Meher un Nissa, κ.ά.
Έκδοση: (2021-07-01)

HSP70 cleavage-induced photoreceptor cell death caused by N-methyl-N-nitrosourea
ανά: Yoshiki Koriyama, κ.ά.
Έκδοση: (2016-01-01)

Genotoxic and chemopreventive potentials of ethanol leaves extract of Annona muricata on N-Ethyl-N-Nitrosourea-induced pro-leukaemia carcinogen in mice model by bone marrow micronucleus assay
ανά: Oluwaseyi Bamisaye, κ.ά.
Έκδοση: (2022-12-01)

Histopathological features of peripheral T-cell lymphoma in Sprague Dawley rats induced with N-methyl-N-nitrosourea
ανά: Al-Salih, Hutheyfa A. H., κ.ά.
Έκδοση: (2011)

Alteration of serum biochemical parameters and urinalysis in Sprague Dawley rats administered with N-methyl-N-nitrosourea
ανά: Hakimi, M. K., κ.ά.
Έκδοση: (2012)

Lycium barbarum glycopeptide (wolfberry extract) slows N-methyl-N-nitrosourea-induced degradation of photoreceptors
ανά: Qihang Kong, κ.ά.
Έκδοση: (2024-01-01)

Short-term carcinogenicity study of N-methyl-N-nitrosourea in FVB-Trp53 heterozygous mice.
ανά: Na-Won Kim, κ.ά.
Έκδοση: (2023-01-01)

Involvement of neuronal nitric oxide synthase in N-methyl-N-nitrosourea-induced retinal degeneration in mice
ανά: Yoshiki Koriyama, κ.ά.
Έκδοση: (2015-03-01)

N-methyl-N-nitrosourea induces zebrafish anomalous angiogenesis through Wnt/β-catenin pathway
ανά: Saifang Fu, κ.ά.
Έκδοση: (2022-07-01)

Preventive effect of Oenothera rosea on N-methyl-N-nitrosourea- (NMU) induced gastric cancer in rats
ανά: Almora-Pinedo Y, κ.ά.
Έκδοση: (2017-12-01)

Role of Oxidative Stress in Retinal Photoreceptor Cell Death in N-Methyl-N-nitrosourea–Treated Mice
ανά: Kazuhiro Tsuruma, κ.ά.
Έκδοση: (2012-01-01)

The reason for the amelioration of N-methyl-N-nitrosourea- induced retinitis pigmentosa in rats by hydrogen-rich saline
ανά: Wei-Ming Yan, κ.ά.
Έκδοση: (2017-10-01)

N-Ethyl-N-Nitrosourea Induced Leukaemia in a Mouse Model: Protective Effect of Icaritin via Inhibition of IL-6/JAK2/STAT3 Pathway Causes Apoptosis
ανά: Hou X, κ.ά.
Έκδοση: (2024-02-01)

ENU-induced phenovariance in mice: inferences from 587 mutations.
ανά: Arnold, C, κ.ά.
Έκδοση: (2012)

ENU-induced phenovariance in mice: inferences from 587 mutations
ανά: Arnold Carrie N, κ.ά.
Έκδοση: (2012-10-01)