Efficient complement-mediated lysis of cells containing the CAMPATH-1 (CDw52) antigen.
CAMPATH-1 antibodies recognise a unique molecule on human lymphocytes and are unusually efficient at causing cell lysis with homologous complement. They have been successfully used for lymphocyte depletion in vivo in a variety of diseases. The antigen is a small glycosylphosphatidylinositol (GPI)-an...
المؤلفون الرئيسيون: | Xia, M, Hale, G, Waldmann, H |
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التنسيق: | Journal article |
اللغة: | English |
منشور في: |
1993
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مواد مشابهة
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The CAMPATH-1 antigen (CDw52).
حسب: Hale, G, وآخرون
منشور في: (1990) -
Characterization of the CAMPATH-1 (CDw52) antigen: biochemical analysis and cDNA cloning reveal an unusually small peptide backbone.
حسب: Xia, M, وآخرون
منشور في: (1991) -
Structure of the CAMPATH-1 antigen, a glycosylphosphatidylinositol-anchored glycoprotein which is an exceptionally good target for complement lysis.
حسب: Xia, M, وآخرون
منشور في: (1993) -
COMPLEMENT LYSIS MEDIATED BY ENGINEERED MULTIPLE-DOMAIN FORMS OF THE THERAPEUTIC ANTIBODY CAMPATH-1H
حسب: Greenwood, J, وآخرون
منشور في: (1994) -
Importance of antigen specificity for complement-mediated lysis by monoclonal antibodies.
حسب: Bindon, C, وآخرون
منشور في: (1988)