Site-selective traceless Staudinger ligation for glycoprotein synthesis reveals scope and limitations.

Making it traceless: A traceless Staudinger reaction between a specifically functionalized sugar phosphine and an azide-tagged protein allows the construction of well-defined reverse N-linked glycoproteins (see scheme). This reaction was applied to different azidoprotein substrates and its potential...

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Detalhes bibliográficos
Principais autores: Bernardes, G, Linderoth, L, Doores, K, Boutureira, O, Davis, B
Formato: Journal article
Idioma:English
Publicado em: 2011